DrugRepV_0020 | Erythromycin | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | GZ01, a recent Asian lineage | NA | Plaque assay | Increase (120 %) | Approved | 29033372 |
DrugRepV_0046 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | H/PF/2013 | NA | Plaque assay | Decrease (50 %) | Approved | 28912011 |
DrugRepV_0047 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | H/PF/2013 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 28912011 |
DrugRepV_0048 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | ZIKVNL00013 | NA | Plaque assay | Decrease (50 %) | Approved | 28912011 |
DrugRepV_0049 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | ZIKVNL00013 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 28912011 |
DrugRepV_0050 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | H/PF/2013 | NA | Plaque assay | No significant effect (0 %) | Approved | 28912011 |
DrugRepV_0051 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | ZIKVNL00013 | NA | Plaque assay | No significant effect (0 %) | Approved | 28912011 |
DrugRepV_0052 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | H/PF/2013 | NA | Cytopathic effect (CPE) assay | No significant effect (0 %) | Approved | 28912011 |
DrugRepV_0053 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | ZIKVNL00013 | NA | Cytopathic effect (CPE) assay | No significant effect (0 %) | Approved | 28912011 |
DrugRepV_0054 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | H/PF/2013 | NA | Plaque assay | No significant effect (0 %) | Approved | 28912011 |
DrugRepV_0055 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | ZIKVNL00013 | NA | Plaque assay | No significant effect (0 %) | Approved | 28912011 |
DrugRepV_0202 | Azithromycin | Antiinfectives For Systemic Use | Microbial infections | Ebola virus | VLP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27890675 |
DrugRepV_0203 | Clarithromycin | Antiinfectives For Systemic Use | Microbial infections | Ebola virus | VLP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27890675 |
DrugRepV_0204 | Posaconazole | Antiinfectives For Systemic Use | Fungal infections (Aspergillus and Candida infections) | Ebola virus | VLP | NA | Immunoflourescence assay | Decrease (50 %) | Approved, Investigational, Vet approved | 27890675 |
DrugRepV_0209 | Posaconazole | Antiinfectives For Systemic Use | Fungal infections (Aspergillus and Candida infections) | Ebola virus | EBOLA/Mayinga-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved, Investigational, Vet approved | 27890675 |
DrugRepV_0211 | Clarithromycin | Antiinfectives For Systemic Use | Microbial infections | Ebola virus | EBOLA/Mayinga-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27890675 |
DrugRepV_0221 | Zidovudine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome/AIDS | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?3.12 ± 0.27 Ct) | Approved | 27801778 |
DrugRepV_0222 | Zidovudine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome/AIDS | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?7.91 ± 2.67 Ct) | Approved | 27801778 |
DrugRepV_0223 | Didanosine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?0.43 ± 3.87 Ct) | Approved | 27801778 |
DrugRepV_0224 | Didanosine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?2.52 ± 1.27 Ct) | Approved | 27801778 |
DrugRepV_0225 | Stavudine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?2.87 ± 0.22 Ct) | Approved, Investigational | 27801778 |
DrugRepV_0226 | Stavudine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?3.93 ± 0.25 Ct) | Approved, Investigational | 27801778 |
DrugRepV_0227 | Abacavir Sulfate | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?1.54 ± 3.26 Ct) | Approved | 27801778 |
DrugRepV_0228 | Abacavir Sulfate | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?3.95 ± 2.69 Ct) | Approved | 27801778 |
DrugRepV_0229 | Entecavir | Antiinfectives For Systemic Use | Hepatitis B virus | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?3.08 ± 0.20 Ct) | Approved | 27801778 |
DrugRepV_0230 | Entecavir | Antiinfectives For Systemic Use | Hepatitis B virus | Ebola virus | ME718-1976/Yambuku-Ecran | NA | Real-time PCR | Increase (?4.44 ± 1.11 Ct) | Approved | 27801778 |
DrugRepV_0270 | Nalidixic Acid | Antiinfectives For Systemic Use | Bacterial infections | Influenza virus | A/New Jersey/15/2007 | | Relative fluorescent unit | Decrease (50 %) | Approved, Investigational | 26833677 |
DrugRepV_0271 | Nalidixic Acid | Antiinfectives For Systemic Use | Bacterial infections | Influenza virus | A/Netherlands/026/2008 | | Relative fluorescent unit | Decrease (50 %) | Approved, Investigational | 26833677 |
DrugRepV_0272 | Nalidixic Acid | Antiinfectives For Systemic Use | Bacterial infections | Influenza virus | A/Netherlands /049/2008 | | Relative fluorescent unit | No significant effect (50 %) | Approved, Investigational | 26833677 |
DrugRepV_0273 | Nalidixic Acid | Antiinfectives For Systemic Use | Bacterial infections | Influenza virus | A/Brisbane/59/2007 | | Relative fluorescent unit | No significant effect (50 %) | Approved, Investigational | 26833677 |
DrugRepV_0274 | Nalidixic Acid | Antiinfectives For Systemic Use | Bacterial infections | Influenza virus | A/New Jersey/15/2007 | | Plaque assay | Decrease (10 %) | Approved, Investigational | 26833677 |
DrugRepV_0275 | Nalidixic Acid | Antiinfectives For Systemic Use | Bacterial infections | Influenza virus | A/Brisbane/59/2007 | | Plaque assay | No significant effect | Approved, Investigational | 26833677 |
DrugRepV_0286 | Imipenem | Antiinfectives For Systemic Use | Bacterial infections | Influenza virus | A/New Jersey/15/2007 | | Relative fluorescent unit | Decrease (50 %) | Approved | 26833677 |
DrugRepV_0287 | Imipenem | Antiinfectives For Systemic Use | Bacterial infections | Influenza virus | A/Netherlands/026/2008 | | Relative fluorescent unit | Decrease (50 %) | Approved | 26833677 |
DrugRepV_0288 | Imipenem | Antiinfectives For Systemic Use | Bacterial infections | Influenza virus | A/Netherlands /049/2008 | | Relative fluorescent unit | Decrease (50 %) | Approved | 26833677 |
DrugRepV_0289 | Imipenem | Antiinfectives For Systemic Use | Bacterial infections | Influenza virus | A/Brisbane /56/2007 | | Relative fluorescent unit | Decrease (50 %) | Approved | 26833677 |
DrugRepV_0290 | Kaletra | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Middle East respiratory syndrome coronavirus | EMC/2012 | NA | Real-time PCR | Decrease (1.06 Log10 Copies/GAPDH) | Approved, Investigational | 26198719 |
DrugRepV_0291 | Kaletra | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Middle East respiratory syndrome coronavirus | EMC/2012 | NA | Immunohistochemical assay | Decrease (>90 %) | Approved, Investigational | 26198719 |
DrugRepV_0321 | Azithromycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0322 | Chlortetracycline | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | EBOV-eGFP | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0342 | Azithromycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus | NA | Renilla luciferase assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0343 | Chlortetracycline | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Ebola Zaire glycoprotein pseudotype vesicular stomatitis virus | NA | Renilla luciferase assay | Decrease (50 %) | Approved | 27622822 |
DrugRepV_0353 | Azithromycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Ebola Zaire | NA | Survival assay | Increase | Approved | 27622822 |
DrugRepV_0354 | Azithromycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Ebola Zaire | NA | Survival assay | No significant effect | Approved | 27622822 |
DrugRepV_0364 | Chlortetracycline | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Ebola Zaire | NA | Survival assay | No significant effect | Approved | 27622822 |
DrugRepV_0365 | Chlortetracycline | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Ebola Zaire | NA | Survival assay | No significant effect | Approved | 27622822 |
DrugRepV_0366 | Azithromycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Ebola Mayinga | NA | Survival assay | No significant effect | Approved | 27622822 |
DrugRepV_0374 | Cilastatin Sodium | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0384 | Flucytosine | Antiinfectives For Systemic Use | Fungal infections | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational | 26041706 |
DrugRepV_0431 | Efavirenz | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0445 | Teicoplanin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0458 | Efavirenz | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0472 | Teicoplanin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | eGFP-EBOV | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26041706 |
DrugRepV_0487 | Efavirenz | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Approved | 26041706 |
DrugRepV_0502 | Teicoplanin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | EBOV-VLP | NA | Flow cytometry | Decrease (>90 %) | Approved | 26041706 |
DrugRepV_0534 | Azithromycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0537 | Clarithromycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0556 | Spiramycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 26038505 |
DrugRepV_0565 | Posaconazole | Antiinfectives For Systemic Use | Fungal infections (Aspergillus and Candida infections) | Ebola virus | EBOVBlaVP40 | NA | Fluorescence-based assay | Decrease (50 %) | Approved, Investigational, Vet approved | 26038505 |
DrugRepV_0580 | Minocycline | Antiinfectives For Systemic Use | Rocky Mountain spotted fever | Typhus fever and the typhus group | Q fever | Rickettsial pox | tick fevers caused by Rickettsiae | Upper respiratory tract infections caused by Streptococcus pneumoniae | Influenza virus | Anhui01 | | Plaque assay | Decrease (1.3 Log10 copies) | Approved, Investigational | 24496798 |
DrugRepV_0615 | Dirithromycin | Antiinfectives For Systemic Use | Bacterial infections | Lassa virus | GP derived Pseudovirus | NA | Luciferase reporter assay | No significant effect (0 %) | Approved | 23577127 |
DrugRepV_0616 | Erythromycin | Antiinfectives For Systemic Use | Bacterial infections | Lassa virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (60 %) | Approved | 23577127 |
DrugRepV_0635 | Dirithromycin | Antiinfectives For Systemic Use | Bacterial infections | Lassa virus | Josiah | NA | Real-time PCR | No significant effect | Approved | 23577127 |
DrugRepV_0636 | Erythromycin | Antiinfectives For Systemic Use | Bacterial infections | Lassa virus | Josiah | NA | Real-time PCR | No significant effect | Approved | 23577127 |
DrugRepV_0654 | Dirithromycin | Antiinfectives For Systemic Use | Bacterial infections | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (91 %) | Approved | 23577127 |
DrugRepV_0655 | Erythromycin | Antiinfectives For Systemic Use | Bacterial infections | Marburg virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (98 %) | Approved | 23577127 |
DrugRepV_0678 | Dirithromycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (99 %) | Approved | 23577127 |
DrugRepV_0679 | Erythromycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | GP derived Pseudovirus | NA | Luciferase reporter assay | Decrease (96 %) | Approved | 23577127 |
DrugRepV_0700 | Dirithromycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | No significant effect | Approved | 23577127 |
DrugRepV_0701 | Erythromycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | EBOLA-eGFP | NA | Fluorescence-based assay | No significant effect | Approved | 23577127 |
DrugRepV_0727 | Dirithromycin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | ma-EBOV | NA | NA | No significant effect | Approved | 23577127 |
DrugRepV_0728 | Erythromycin ethylsuccinate | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | ma-EBOV | NA | NA | No significant effect | Approved | 23577127 |
DrugRepV_0760 | Clofazimine | Antiinfectives For Systemic Use | Lepromatous leprosy | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (99.665 %) | Approved | 27476412 |
DrugRepV_0782 | Daptomycin | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (89.915 %) | Approved | 27476412 |
DrugRepV_0785 | Micafungin | Antiinfectives For Systemic Use | Fungal infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (86.88 %) | Approved, Investigational | 27476412 |
DrugRepV_0803 | Posaconazole | Antiinfectives For Systemic Use | Fungal infections (Aspergillus and Candida infections) | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (61.34 %) | Approved, Investigational, Vet approved | 27476412 |
DrugRepV_0839 | Isoniazid | Antiinfectives For Systemic Use | Tuberculosis | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (60.29 %) | Approved, Investigational | 27476412 |
DrugRepV_0843 | Penicillin G Potassium | Antiinfectives For Systemic Use | Septicemia | Meningitis | Pericarditis | Endocarditis | Pneumonia | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (52.15 %) | Approved | 27476412 |
DrugRepV_0846 | Cefuroxime Axetil | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (55.5 %) | Approved | 27476412 |
DrugRepV_0852 | Linezolid | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (60.395 %) | Approved, Investigational | 27476412 |
DrugRepV_0856 | Lincomycin Hydrochloride | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (58.795 %) | Approved, Vet approved | 27476412 |
DrugRepV_0859 | Nelfinavir Mesylate | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (60.53 %) | Approved | 27476412 |
DrugRepV_0870 | Erythromycin | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (55.1 %) | Approved | 27476412 |
DrugRepV_0876 | Norfloxacin | Antiinfectives For Systemic Use | Urinary tract infection | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (57.51 %) | Approved | 27476412 |
DrugRepV_0878 | Amphotericin B | Antiinfectives For Systemic Use | Fungal infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (54.04 %) | Approved | 27476412 |
DrugRepV_0886 | Ketoconazole | Antiinfectives For Systemic Use | Fungal infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (60.415 %) | Approved, Investigational | 27476412 |
DrugRepV_0888 | Ceftibuten | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (53.895 %) | Approved | 27476412 |
DrugRepV_0901 | Efavirenz | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (57.92 %) | Approved | 27476412 |
DrugRepV_0907 | Ofloxacin | Antiinfectives For Systemic Use | Respiratory tract infections | Kidney infection | Skin infection | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (55.695 %) | Approved | 27476412 |
DrugRepV_0909 | Penciclovir | Antiinfectives For Systemic Use | Recurrent cold sores on the lips and face from Herpesvirus invections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (55.495 %) | Approved | 27476412 |
DrugRepV_0923 | Amikacin Disulfate | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (52.975 %) | Approved | 27476412 |
DrugRepV_0924 | Ciprofloxacin | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (55.87 %) | Approved | 27476412 |
DrugRepV_0926 | Spectinomycin Hydrochloride Pentahydrate | Antiinfectives For Systemic Use | Bacterial infections (Gonorrheal urethritis and proctitis) | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (55.825 %) | Approved, Investigational, Vet approved | 27476412 |
DrugRepV_0937 | Penicillin V Potassium | Antiinfectives For Systemic Use | Mild to moderately severe infections due to penicillin G-sensitive microorganisms | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (52.165 %) | Approved | 27476412 |
DrugRepV_0938 | Ceftriaxone Sodium | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (55.04 %) | Approved | 27476412 |
DrugRepV_0963 | Zanamivir | Antiinfectives For Systemic Use | Influenza virus | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (47.235 %) | Approved | 27476412 |
DrugRepV_0968 | Ethionamide | Antiinfectives For Systemic Use | Tuberculosis | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (52.99 %) | Approved | 27476412 |
DrugRepV_0974 | Oxacillin Sodium salt Monohydrate | Antiinfectives For Systemic Use | Staphylococci infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (54.525 %) | Approved, Investigational | 27476412 |
DrugRepV_0982 | Cefixime | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (48.925 %) | Approved | 27476412 |
DrugRepV_0986 | Pyrazinamide | Antiinfectives For Systemic Use | Tuberculosis | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (50.975 %) | Approved, Investigational | 27476412 |
DrugRepV_1001 | Delavirdine Mesylate | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (54.035 %) | Approved | 27476412 |
DrugRepV_1012 | Cefaclor | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (50.11 %) | Approved | 27476412 |
DrugRepV_1015 | Chloramphenicol | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (54.08 %) | Approved | 27476412 |
DrugRepV_1020 | Cidofovir | Antiinfectives For Systemic Use | Cytomegalovirus infection | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (53.06 %) | Approved | 27476412 |
DrugRepV_1021 | Levofloxacin Hydrochloride | Antiinfectives For Systemic Use | Bacterial infections (Conjunctivitis) | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (51.885 %) | Approved | 27476412 |
DrugRepV_1022 | Demeclocycline Hydrochloride | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (50.41 %) | Approved | 27476412 |
DrugRepV_1026 | Cefuroxime Sodium | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (52.005 %) | Approved | 27476412 |
DrugRepV_1029 | Ethambutol Dihydrochloride | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (49.32 %) | Approved | 27476412 |
DrugRepV_1035 | Doxycycline Monohydrate | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (52.935 %) | Approved | 27476412 |
DrugRepV_1043 | Voriconazole | Antiinfectives For Systemic Use | Fungal infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (52.235 %) | Approved | 27476412 |
DrugRepV_1045 | Dapsone | Antiinfectives For Systemic Use | Leprosy and dermatitis herpetiformis | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (48.585 %) | Approved | 27476412 |
DrugRepV_1053 | Bacitracin | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (47.205 %) | Approved | 27476412 |
DrugRepV_1055 | Ceftizoxim Sodium | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (52.58 %) | Approved | 27476412 |
DrugRepV_1075 | Cefotaxime Acid | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (54.85 %) | Approved | 27476412 |
DrugRepV_1076 | Lopinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (55 %) | Approved | 27476412 |
DrugRepV_1078 | Clindamycin Hydrochloride | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (51.415 %) | Approved | 27476412 |
DrugRepV_1084 | Gemifloxacin | Antiinfectives For Systemic Use | Bacterial infections (Chronic bronchitis and mild-to-moderate pneumonia) | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (51.92 %) | Approved, Investigational | 27476412 |
DrugRepV_1085 | Adefovir dipivoxil | Antiinfectives For Systemic Use | Hepatitis B virus | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (52.3 %) | Approved | 27476412 |
DrugRepV_1090 | Cefprozil | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (46.765 %) | Approved | 27476412 |
DrugRepV_1095 | Emtricitabine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (51.065 %) | Approved | 27476412 |
DrugRepV_1096 | Cefdinir | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (47.845 %) | Approved | 27476412 |
DrugRepV_1103 | Cycloserine | Antiinfectives For Systemic Use | Tuberculosis | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (47.77 %) | Approved | 27476412 |
DrugRepV_1109 | Tenofovir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (44.855 %) | Approved, Investigational | 27476412 |
DrugRepV_1111 | Moxifloxacin Hydrochloride | Antiinfectives For Systemic Use | Sinusitis | Pneumonia | Chronic bronchitis | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (53.71 %) | Approved, Investigational | 27476412 |
DrugRepV_1113 | Oxytetracycline Hydrochloride | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (46.71 %) | Approved, Investigational, Vet approved | 27476412 |
DrugRepV_1116 | Valganciclovir Hydrochloride | Antiinfectives For Systemic Use | Herpes simplex and Zoster virus | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (49.32 %) | Approved | 27476412 |
DrugRepV_1118 | 4-Aminosalicylic Acid | Antiinfectives For Systemic Use | Tuberculosis | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (51.44 %) | Approved | 27476412 |
DrugRepV_1131 | Methenamine Hippurate | Antiinfectives For Systemic Use | Urinary tract infection | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (52.645 %) | Approved, Vet approved | 27476412 |
DrugRepV_1132 | Cloxacillin Sodium | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (49.82 %) | Approved | 27476412 |
DrugRepV_1148 | Piperacillin | Antiinfectives For Systemic Use | Polymicrobial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (47.9 %) | Approved | 27476412 |
DrugRepV_1151 | Famciclovir | Antiinfectives For Systemic Use | Herpes simplex virus | Zoster virus | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (47.62 %) | Approved, Investigational | 27476412 |
DrugRepV_1157 | Amoxicillin | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (49.335 %) | Approved | 27476412 |
DrugRepV_1163 | Sulfanilamide | Antiinfectives For Systemic Use | Vulvovaginitis | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (47.175 %) | Approved | 27476412 |
DrugRepV_1165 | Rifampin | Antiinfectives For Systemic Use | Tuberculosis and Tuberculosis-related mycobacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (52.505 %) | Approved | 27476412 |
DrugRepV_1167 | Cefepime Hydrochloride Hydrate | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (52.89 %) | Approved | 27476412 |
DrugRepV_1177 | Doripenem | Antiinfectives For Systemic Use | Intra-abdominal infections and complicated urinary tract infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (47.47 %) | Approved | 27476412 |
DrugRepV_1187 | Cefadroxil | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (48.15 %) | Approved | 27476412 |
DrugRepV_1189 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (49.03 %) | Approved | 27476412 |
DrugRepV_1191 | Dicloxacillin Sodium Salt Monohydrate | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (46.765 %) | Approved | 27476412 |
DrugRepV_1196 | Ganciclovir | Antiinfectives For Systemic Use | Cytomegalovirus infection | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (49.48 %) | Approved, Investigational | 27476412 |
DrugRepV_1209 | Maraviroc | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (48.18 %) | Approved, Investigational | 27476412 |
DrugRepV_1212 | Zalcitabine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome/AIDS | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (49.06 %) | Approved | 27476412 |
DrugRepV_1216 | Kanamycin Sulfate | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (46.43 %) | Approved, Investigational, Vet approved | 27476412 |
DrugRepV_1225 | Nevirapine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (47.07 %) | Approved | 27476412 |
DrugRepV_1227 | Darunavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (44.605 %) | Approved | 27476412 |
DrugRepV_1234 | Cefotetan Disodium | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (47.645 %) | Approved | 27476412 |
DrugRepV_1235 | Aztreonam | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (46.05 %) | Approved | 27476412 |
DrugRepV_1238 | Flucytosine | Antiinfectives For Systemic Use | Fungal infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (48.75 %) | Approved, Investigational | 27476412 |
DrugRepV_1247 | Minocycline | Antiinfectives For Systemic Use | Rocky Mountain spotted fever | Typhus fever and the typhus group | Q fever | Rickettsial pox | tick fevers caused by Rickettsiae | Upper respiratory tract infections caused by Streptococcus pneumoniae | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (46.405 %) | Approved, Investigational | 27476412 |
DrugRepV_1261 | Ritonavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (40.915 %) | Approved, Investigational | 27476412 |
DrugRepV_1262 | Cefditoren Pivoxil | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (46.4 %) | Approved | 27476412 |
DrugRepV_1264 | Cefpodoxime Proxetil | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (46.81 %) | Approved | 27476412 |
DrugRepV_1271 | Meropenem | Antiinfectives For Systemic Use | Bacterial infections (Skin infection) | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (48.025 %) | Approved, Investigational | 27476412 |
DrugRepV_1274 | Lamivudine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Hepatitis B virus | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (45.2 %) | Approved, Investigational | 27476412 |
DrugRepV_1276 | Tigecycline | Antiinfectives For Systemic Use | Complicated skin and skin structure infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (46.4 %) | Approved | 27476412 |
DrugRepV_1281 | Clarithromycin | Antiinfectives For Systemic Use | Microbial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (49.09 %) | Approved | 27476412 |
DrugRepV_1282 | Fosfomycin Calcium | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (45.385 %) | Approved | 27476412 |
DrugRepV_1288 | Trimethoprim | Antiinfectives For Systemic Use | Urinary tract infections | Uncomplicated pyelonephritis (with sulfamethoxazole) | Mild acute prostatitis | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (49.69 %) | Approved | 27476412 |
DrugRepV_1295 | Cilastatin Sodium | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (49.065 %) | Approved | 27476412 |
DrugRepV_1302 | Stavudine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (45.29 %) | Approved, Investigational | 27476412 |
DrugRepV_1307 | Neomycin Sulfate | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (47.33 %) | Approved | 27476412 |
DrugRepV_1309 | Nafcillin Sodium | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (42.57 %) | Approved, Investigational | 27476412 |
DrugRepV_1310 | Capreomycin Disulfate | Antiinfectives For Systemic Use | Tuberculosis | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (46.425 %) | Approved | 27476412 |
DrugRepV_1321 | Sulfamethoxazole | Antiinfectives For Systemic Use | Bacterial infections (Bronchitis, prostatitis and urinary tract infections) | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (43.87 %) | Approved | 27476412 |
DrugRepV_1325 | Tetracycline | Antiinfectives For Systemic Use | Bacterial infections (Rocky Mountain spotted fever | Typhus fever | Tick fevers | Q fever | Rickettsialpox | Brill-Zinsser disease) | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (49.51 %) | Approved | 27476412 |
DrugRepV_1326 | Sulfadiazine | Antiinfectives For Systemic Use | Rheumatic fever | Meningococcal meningitis | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (48.975 %) | Approved, Investigational, Vet approved | 27476412 |
DrugRepV_1340 | Itraconazole | Antiinfectives For Systemic Use | Fungal infections (Pulmonary and extrapulmonary blastomycosis, Histoplasmosis, Aspergillosis, and Onychomycosis) | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (47.185 %) | Approved, Investigational | 27476412 |
DrugRepV_1352 | Gatifloxacin | Antiinfectives For Systemic Use | Bacterial infections (Bronchitis, sinusitis, Community-acquired pneumonia, and Skin infections) | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (45.98 %) | Approved, Investigational | 27476412 |
DrugRepV_1362 | Zidovudine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome/AIDS | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (46.965 %) | Approved | 27476412 |
DrugRepV_1364 | Telbivudine | Antiinfectives For Systemic Use | Hepatitis B virus | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (44.765 %) | Approved | 27476412 |
DrugRepV_1369 | Fluconazole | Antiinfectives For Systemic Use | Fungal infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (40.98 %) | Approved, Investigational | 27476412 |
DrugRepV_1371 | Azithromycin | Antiinfectives For Systemic Use | Microbial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (44.07 %) | Approved | 27476412 |
DrugRepV_1380 | Ampicillin Trihydrate | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (46.895 %) | Approved | 27476412 |
DrugRepV_1382 | Foscarnet Sodium | Antiinfectives For Systemic Use | Cytomegalovirus retinitis | Herpesviruses | Acquired immunodeficiency syndrome | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (42.945 %) | Approved | 27476412 |
DrugRepV_1391 | Nitrofurantoin | Antiinfectives For Systemic Use | Urinary tract infection | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (45.26 %) | Approved | 27476412 |
DrugRepV_1392 | Abacavir Sulfate | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (45.76 %) | Approved | 27476412 |
DrugRepV_1416 | Rifapentine | Antiinfectives For Systemic Use | Tuberculosis | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (41.79 %) | Approved, Investigational | 27476412 |
DrugRepV_1433 | Idoxuridine | Antiinfectives For Systemic Use | Keratoconjunctivitis and Keratitis caused by herpes simplex virus | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (42.78 %) | Approved, Investigational | 27476412 |
DrugRepV_1444 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (43.21 %) | Approved | 27476412 |
DrugRepV_1450 | Valacyclovir Hydrochloride | Antiinfectives For Systemic Use | Herpes simplex and Zoster virus | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (44.35 %) | Approved | 27476412 |
DrugRepV_1454 | Didanosine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (40.17 %) | Approved | 27476412 |
DrugRepV_1457 | Imipenem | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (42.8 %) | Approved | 27476412 |
DrugRepV_1460 | Indinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (42.985 %) | Approved | 27476412 |
DrugRepV_1478 | Atazanavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (38.68 %) | Approved | 27476412 |
DrugRepV_1482 | Rifabutin | Antiinfectives For Systemic Use | Mycobacterium avium complex (MAC) disease in patients with advanced Acquired immunodeficiency syndrome infection | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (35.56 %) | Approved, Investigational | 27476412 |
DrugRepV_1486 | Oseltamivir Phosphate | Antiinfectives For Systemic Use | Influenza A/B virus | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (44.305 %) | Approved | 27476412 |
DrugRepV_1501 | Rimantadine Hydrochloride | Antiinfectives For Systemic Use | Influenza A virus | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (39.755 %) | Approved, Investigational | 27476412 |
DrugRepV_1516 | Saquinavir Mesylate | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (32.635 %) | Approved, Investigational | 27476412 |
DrugRepV_1517 | Telithromycin | Antiinfectives For Systemic Use | Pneumococcal infection | Acute sinusitis | Acute bacterial tonsillitis | Acute bronchitis and bronchiolitis | Lower respiratory tract infection and lobar (pneumococcal) pneumonia | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (31.37 %) | Approved | 27476412 |
DrugRepV_1522 | Streptomycin Sulfate | Antiinfectives For Systemic Use | Tuberculosis | Tularemia | Plague | Brucellosis | Endocarditis | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (28.56 %) | Approved, Vet approved | 27476412 |
DrugRepV_1530 | Clindamycin Palmitate Hydrochloride | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (22.29 %) | Approved | 27476412 |
DrugRepV_1534 | Daptomycin | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Flow cytometry | Decrease (50 %) | Approved | 27476412 |
DrugRepV_1541 | Daptomycin | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Flow cytometry | No significant effect (50 %) | Approved | 27476412 |
DrugRepV_1545 | Daptomycin | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Flow cytometry | Increase (120 %) | Approved | 27476412 |
DrugRepV_1550 | Daptomycin | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | DAK_41525 | NA | Flow cytometry | No significant effect | Approved | 27476412 |
DrugRepV_1557 | Daptomycin | Antiinfectives For Systemic Use | Bacterial infections | Zika virus | MEX_I_7 | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 27476412 |
DrugRepV_1576 | Itraconazole | Antiinfectives For Systemic Use | Fungal infections (Pulmonary and extrapulmonary blastomycosis, Histoplasmosis, Aspergillosis, and Onychomycosis) | Rift Valley fever virus | MP12-Luc | NA | Luciferase reporter assay | Decrease (74 %) | Approved, Investigational | 26217313 |
DrugRepV_1592 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Rift Valley fever virus | rMP12 | NA | Plaque assay | Decrease (4 Logs reduction) | Approved | 26217313 |
DrugRepV_1594 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Rift Valley fever virus | rMP12 | NA | Plaque assay | Decrease (4.5 Logs reduction) | Approved | 26217313 |
DrugRepV_1596 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Rift Valley fever virus | rMP12 | NA | Plaque assay | Decrease (1 Logs reduction) | Approved | 26217313 |
DrugRepV_1598 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Rift Valley fever virus | rMP12 | NA | Plaque assay | Decrease (3 Logs reduction) | Approved | 26217313 |
DrugRepV_1600 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Rift Valley fever virus | rMP12 | NA | Plaque assay | Decrease (4 Logs reduction) | Approved | 26217313 |
DrugRepV_1602 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Rift Valley fever virus | rMP12 | NA | Plaque assay | Decrease (6 Logs reduction) | Approved | 26217313 |
DrugRepV_1604 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Rift Valley fever virus | rMP12 | NA | Plaque assay | Decrease (2 Logs reduction) | Approved | 26217313 |
DrugRepV_1606 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Rift Valley fever virus | rMP12 | NA | Plaque assay | Decrease (5 Logs reduction) | Approved | 26217313 |
DrugRepV_1608 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Rift Valley fever virus | rMP12 | NA | Plaque assay | Decrease (100 %) | Approved | 26217313 |
DrugRepV_1622 | Minocycline | Antiinfectives For Systemic Use | Rocky Mountain spotted fever | Typhus fever and the typhus group | Q fever | Rickettsial pox | tick fevers caused by Rickettsiae | Upper respiratory tract infections caused by Streptococcus pneumoniae | Influenza virus | A/Anhui/01/2013 | | Transcriptomic response-DEG | Decrease | Approved, Investigational | 24991006 |
DrugRepV_1930 | Nelfinavir Mesylate | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Zika virus | H/PF/2013 | NA | Plaque assay | Decrease (2 Logs) | Approved | 28814523 |
DrugRepV_1935 | Nelfinavir Mesylate | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Zika virus | H/PF/2013 | NA | Real-time PCR | Decrease (0 %) | Approved | 28814523 |
DrugRepV_1940 | Nelfinavir Mesylate | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Zika virus | H/PF/2013 | NA | Immunoflourescence assay | Decrease | Approved | 28814523 |
DrugRepV_2015 | Teicoplanin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (50 %) | Approved | 26585243 |
DrugRepV_2030 | Teicoplanin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (90 %) | Approved | 26585243 |
DrugRepV_2031 | Teicoplanin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (50 %) | Approved | 26585243 |
DrugRepV_2032 | Teicoplanin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (87.5 %) | Approved | 26585243 |
DrugRepV_2033 | Teicoplanin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | Decrease (95 %) | Approved | 26585243 |
DrugRepV_2034 | Teicoplanin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | Zaire strain-pEBOV | NA | Firefly luciferase assay | No significant effect (0 %) | Approved | 26585243 |
DrugRepV_2038 | Lopinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Middle East respiratory syndrome coronavirus | EMC/2012 | NA | Cell viability assay | Decrease (50 %) | Approved | 24841269 |
DrugRepV_2042 | Lopinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Severe acute respiratory syndrome coronavirus | NA | NA | Cell viability assay | Decrease (50 %) | Approved | 24841269 |
DrugRepV_2046 | Lopinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Severe acute respiratory syndrome coronavirus | 229E-GFP | NA | Cell viability assay | Decrease (50 %) | Approved | 24841269 |
DrugRepV_2052 | Rifabutin | Antiinfectives For Systemic Use | Mycobacterium avium complex (MAC) disease in patients with advanced Acquired immunodeficiency syndrome infection | Middle East respiratory syndrome coronavirus | EMC/2012 | NA | Cell viability assay | No significant decrease (10 %) | Approved, Investigational | 24841269 |
DrugRepV_2053 | Rifapentine | Antiinfectives For Systemic Use | Tuberculosis | Middle East respiratory syndrome coronavirus | EMC/2012 | NA | Cell viability assay | Decrease (50 %) | Approved, Investigational | 24841269 |
DrugRepV_2113 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | PRVABC-59 | NA | Plaque assay | Decrease (50 %) | Approved | 27902933 |
DrugRepV_2114 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | PRVABC-59 | NA | Plaque assay | Decrease (50 %) | Approved | 27902933 |
DrugRepV_2115 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | Paraiba | NA | Plaque assay | Decrease (50 %) | Approved | 27902933 |
DrugRepV_2116 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | Paraiba | NA | Plaque assay | Decrease (50 %) | Approved | 27902933 |
DrugRepV_2117 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | Dakar | NA | Plaque assay | Decrease (50 %) | Approved | 27902933 |
DrugRepV_2118 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | Dakar | NA | Plaque assay | Decrease (50 %) | Approved | 27902933 |
DrugRepV_2119 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | PRVABC-59 | NA | Real-time PCR | Decrease (>1 Log10 (GE/ml)) | Approved | 27902933 |
DrugRepV_2120 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | PRVABC-59 | NA | Real-time PCR | Decrease (2 Log10 (GE/ml)) | Approved | 27902933 |
DrugRepV_2121 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | Paraiba | NA | Real-time PCR | Decrease (>1 Log10 (GE/ml)) | Approved | 27902933 |
DrugRepV_2122 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | Paraiba | NA | Real-time PCR | Decrease (2 Log10 (GE/ml)) | Approved | 27902933 |
DrugRepV_2123 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | Dakar | NA | Real-time PCR | Decrease (>1 Log10 (GE/ml)) | Approved | 27902933 |
DrugRepV_2124 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | Dakar | NA | Real-time PCR | Decrease (>2 Log10 (GE/ml)) | Approved | 27902933 |
DrugRepV_2125 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | Paraiba | NA | Flow cytometry | Decrease (50 %) | Approved | 27902933 |
DrugRepV_2126 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | Paraiba | NA | Flow cytometry | Decrease (50 %) | Approved | 27902933 |
DrugRepV_2127 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | Dakar/41519 | NA | Survival assay | Increase | Approved | 27902933 |
DrugRepV_2128 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | MR766 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 27163257 |
DrugRepV_2129 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | MR766 | NA | Virus yield reduction assay | Decrease (50 %) | Approved | 27163257 |
DrugRepV_2198 | Neomycin Sulfate | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (10.0220837 %) | Approved | 27742486 |
DrugRepV_2200 | Rifampin | Antiinfectives For Systemic Use | Tuberculosis and Tuberculosis-related mycobacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (9.11795232 %) | Approved | 27742486 |
DrugRepV_2201 | Atazanavir Sulfate | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (8.91119067 %) | Approved | 27742486 |
DrugRepV_2210 | Pefloxacin Mesylate | Antiinfectives For Systemic Use | Gonococcal urethritis in males | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (7.83586814 %) | Approved | 27742486 |
DrugRepV_2214 | Moroxydine | Antiinfectives For Systemic Use | Influenza | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (7.65475751 %) | Experimental | 27742486 |
DrugRepV_2231 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (6.95397975 %) | Approved | 27742486 |
DrugRepV_2240 | Itraconazole | Antiinfectives For Systemic Use | Fungal infections (Pulmonary and extrapulmonary blastomycosis, Histoplasmosis, Aspergillosis, and Onychomycosis) | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (6.35827197 %) | Approved, Investigational | 27742486 |
DrugRepV_2245 | Methenamine | Antiinfectives For Systemic Use | Urinary tract infection | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (6.11366498 %) | Approved, Vet approved | 27742486 |
DrugRepV_2246 | Azithromycin | Antiinfectives For Systemic Use | Microbial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (6.11366498 %) | Approved | 27742486 |
DrugRepV_2258 | Biapenem | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (5.72083061 %) | Investigational | 27742486 |
DrugRepV_2263 | Idoxuridine | Antiinfectives For Systemic Use | Keratoconjunctivitis and Keratitis caused by herpes simplex virus | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (5.28034643 %) | Approved, Investigational | 27742486 |
DrugRepV_2265 | Clindamycin Phosphate | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (5.23907349 %) | Approved | 27742486 |
DrugRepV_2269 | Tigecycline | Antiinfectives For Systemic Use | Complicated skin and skin structure infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (5.03969688 %) | Approved | 27742486 |
DrugRepV_2282 | Doripenem Hydrate | Antiinfectives For Systemic Use | Intra-abdominal infections and complicated urinary tract infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (4.71564204 %) | Approved | 27742486 |
DrugRepV_2283 | Sulfamethazine | Antiinfectives For Systemic Use | Bacterial infections (Bronchitis, prostatitis and urinary tract infections) | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (4.70881807 %) | Approved, Investigational, Vet approved | 27742486 |
DrugRepV_2299 | Sulfapyridine | Antiinfectives For Systemic Use | Dermatitis herpetiformis | Benign mucous membrane pemphigoid | Pyoderma gangrenosum | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (4.40977237 %) | Approved | 27742486 |
DrugRepV_2301 | Thiamphenicol | Antiinfectives For Systemic Use | Infectious diseases in cattle, pigs and poultry) | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (4.40312446 %) | Experimental, Investigational | 27742486 |
DrugRepV_2310 | Sulfamethizole | Antiinfectives For Systemic Use | Urinary tract infection | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (4.08218845 %) | Approved, Investigational, Vet approved | 27742486 |
DrugRepV_2313 | Ritonavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (3.98622242 %) | Approved, Investigational | 27742486 |
DrugRepV_2314 | Lopinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (3.96247894 %) | Approved | 27742486 |
DrugRepV_2324 | Isoniazid | Antiinfectives For Systemic Use | Tuberculosis | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (3.74356574 %) | Approved, Investigational | 27742486 |
DrugRepV_2328 | Ketoconazole | Antiinfectives For Systemic Use | Fungal infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (3.68563359 %) | Approved, Investigational | 27742486 |
DrugRepV_2338 | Posaconazole | Antiinfectives For Systemic Use | Fungal infections (Aspergillus and Candida infections) | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (3.43393568 %) | Approved, Investigational, Vet approved | 27742486 |
DrugRepV_2343 | Protionamide | Antiinfectives For Systemic Use | MDR-TB | Acquired immunodeficiency syndrome | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (3.29332873 %) | Approved, Investigational | 27742486 |
DrugRepV_2347 | Amoxicillin Sodium | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (3.26461637 %) | Approved | 27742486 |
DrugRepV_2354 | Cephradine | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (3.17042436 %) | Approved | 27742486 |
DrugRepV_2358 | Sitafloxacin Hydrate | Antiinfectives For Systemic Use | Bacterial infections (respiratory and urinary tract infections) | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (2.96036077 %) | Experimental, Investigational | 27742486 |
DrugRepV_2360 | Enoxacin | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (2.93176568 %) | Approved | 27742486 |
DrugRepV_2368 | Ampicillin Sodium | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (2.75763916 %) | Approved | 27742486 |
DrugRepV_2383 | Bacitracin Zinc | Antiinfectives For Systemic Use | Pneumonia and empyema | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (2.42855269 %) | Approved | 27742486 |
DrugRepV_2403 | Clindamycin Hydrochloride | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (2.19411786 %) | Approved | 27742486 |
DrugRepV_2404 | Spectinomycin Hydrochloride | Antiinfectives For Systemic Use | Bacterial infections (Gonorrheal urethritis and proctitis) | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (2.18634054 %) | Approved, Investigational, Vet approved | 27742486 |
DrugRepV_2424 | Sulfameter | Antiinfectives For Systemic Use | Leprosy | Urinary | Respiratory tract infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (1.81863222 %) | Approved | 27742486 |
DrugRepV_2426 | Norfloxacin | Antiinfectives For Systemic Use | Urinary tract infection | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (1.69457675 %) | Approved | 27742486 |
DrugRepV_2438 | Rimantadine | Antiinfectives For Systemic Use | Influenza A virus | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (1.43192971 %) | Approved, Investigational | 27742486 |
DrugRepV_2439 | Rifapentine | Antiinfectives For Systemic Use | Tuberculosis | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (1.3653391 %) | Approved, Investigational | 27742486 |
DrugRepV_2445 | Gatifloxacin | Antiinfectives For Systemic Use | Bacterial infections (Bronchitis, sinusitis, Community-acquired pneumonia, and Skin infections) | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (1.22310404 %) | Approved, Investigational | 27742486 |
DrugRepV_2447 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (1.14736269 %) | Approved | 27742486 |
DrugRepV_2448 | Cefoperazone | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (1.13001149 %) | Approved | 27742486 |
DrugRepV_2449 | Tetracycline Hydrochloride | Antiinfectives For Systemic Use | Bacterial infections (Rocky Mountain spotted fever | Typhus fever | Tick fevers | Q fever | Rickettsialpox | Brill-Zinsser disease) | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (1.08422039 %) | Approved, Vet approved | 27742486 |
DrugRepV_2455 | Sulphadimethoxine | Antiinfectives For Systemic Use | Respiratory infection | Urinary tract infection | Enteric infection | Soft tissue infection | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (0.99278461 %) | Approved, Vet approved | 27742486 |
DrugRepV_2457 | Amikacin Hydrate | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (0.87227544 %) | Approved | 27742486 |
DrugRepV_2459 | Pyrazinamide | Antiinfectives For Systemic Use | Tuberculosis | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (0.85917346 %) | Approved, Investigational | 27742486 |
DrugRepV_2476 | Ethionamide | Antiinfectives For Systemic Use | Tuberculosis | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (0.45109184 %) | Approved | 27742486 |
DrugRepV_2478 | Streptomycin Sulfate | Antiinfectives For Systemic Use | Tuberculosis | Tularemia | Plague | Brucellosis | Endocarditis | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (0.42772783 %) | Approved, Vet approved | 27742486 |
DrugRepV_2486 | Cefditoren Pivoxil | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | No significant decrease (0.31336219 %) | Approved | 27742486 |
DrugRepV_2510 | Maraviroc | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-0.0137712 %) | Approved, Investigational | 27742486 |
DrugRepV_2511 | Carbenicillin Disodium | Antiinfectives For Systemic Use | Urinary tract infection | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-0.0151285 %) | Approved | 27742486 |
DrugRepV_2517 | Clarithromycin | Antiinfectives For Systemic Use | Microbial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-0.1486584 %) | Approved | 27742486 |
DrugRepV_2518 | Ganciclovir | Antiinfectives For Systemic Use | Cytomegalovirus infection | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-0.183847 %) | Approved, Investigational | 27742486 |
DrugRepV_2530 | Moxifloxacin Hydrochloride | Antiinfectives For Systemic Use | Sinusitis | Pneumonia | Chronic bronchitis | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-0.5365847 %) | Approved, Investigational | 27742486 |
DrugRepV_2531 | Meropenem | Antiinfectives For Systemic Use | Bacterial infections (Skin infection) | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-0.5411877 %) | Approved, Investigational | 27742486 |
DrugRepV_2540 | Valacyclovir Hydrochloride | Antiinfectives For Systemic Use | Herpes simplex and Zoster virus | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-0.6677761 %) | Approved | 27742486 |
DrugRepV_2543 | Cefaclor | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-0.7251215 %) | Approved | 27742486 |
DrugRepV_2546 | Ciprofloxacin | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-0.8107955 %) | Approved | 27742486 |
DrugRepV_2554 | Oxytetracycline dihydrate | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-0.9136131 %) | Approved, Investigational, Vet approved | 27742486 |
DrugRepV_2557 | Aztreonam | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-0.9905633 %) | Approved | 27742486 |
DrugRepV_2566 | Lincomycin Hydrochloride | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-1.1874718 %) | Approved, Vet approved | 27742486 |
DrugRepV_2568 | Oxacillin Sodium Monohydrate | Antiinfectives For Systemic Use | Staphylococci infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-1.2220202 %) | Approved, Investigational | 27742486 |
DrugRepV_2569 | Entecavir Hydrate | Antiinfectives For Systemic Use | Hepatitis B virus | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-1.2373625 %) | Approved | 27742486 |
DrugRepV_2575 | Amprenavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-1.2615469 %) | Approved | 27742486 |
DrugRepV_2584 | Flumequine | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-1.3882128 %) | Withdrawn | 27742486 |
DrugRepV_2598 | Telbivudine | Antiinfectives For Systemic Use | Hepatitis B virus | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-1.5369604 %) | Approved | 27742486 |
DrugRepV_2606 | Lomefloxacin Hydrochloride | Antiinfectives For Systemic Use | Bacterial infections (respiratory tract (chronic bronchitis) and urinary tract) | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-1.6544832 %) | Approved, Investigational | 27742486 |
DrugRepV_2607 | Linezolid | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-1.6567659 %) | Approved, Investigational | 27742486 |
DrugRepV_2609 | Nevirapine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-1.6918978 %) | Approved | 27742486 |
DrugRepV_2626 | Voriconazole | Antiinfectives For Systemic Use | Fungal infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-1.8244532 %) | Approved | 27742486 |
DrugRepV_2640 | Levofloxacin | Antiinfectives For Systemic Use | Bacterial infections (Conjunctivitis) | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-2.028788 %) | Approved, Investigational | 27742486 |
DrugRepV_2645 | Cidofovir | Antiinfectives For Systemic Use | Cytomegalovirus infection | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-2.1015434 %) | Approved | 27742486 |
DrugRepV_2653 | Fluconazole | Antiinfectives For Systemic Use | Fungal infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-2.2384772 %) | Approved, Investigational | 27742486 |
DrugRepV_2654 | Trimethoprim | Antiinfectives For Systemic Use | Urinary tract infections | Uncomplicated pyelonephritis (with sulfamethoxazole) | Mild acute prostatitis | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-2.2572502 %) | Approved | 27742486 |
DrugRepV_2667 | Azlocillin Sodium salt | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-2.4022354 %) | Approved | 27742486 |
DrugRepV_2673 | Cefprozil Hydrate | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-2.4845708 %) | Approved | 27742486 |
DrugRepV_2685 | Oseltamivir phosphate | Antiinfectives For Systemic Use | Influenza A/B virus | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-2.6044621 %) | Approved | 27742486 |
DrugRepV_2689 | Daptomycin | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-2.764086 %) | Approved | 27742486 |
DrugRepV_2693 | Cloxacillin Sodium | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-2.8753795 %) | Approved | 27742486 |
DrugRepV_2697 | Fleroxacin | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-2.9243945 %) | Experimental | 27742486 |
DrugRepV_2700 | Tenofovir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-2.9691678 %) | Approved, Investigational | 27742486 |
DrugRepV_2704 | Sulbactam Sodium | Antiinfectives For Systemic Use | Bacterial infections (Skin infection) | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-3.0092385 %) | Approved | 27742486 |
DrugRepV_2706 | Sulfadiazine | Antiinfectives For Systemic Use | Rheumatic fever | Meningococcal meningitis | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-3.0259808 %) | Approved, Investigational, Vet approved | 27742486 |
DrugRepV_2710 | D-Cycloserine | Antiinfectives For Systemic Use | Antibiotic | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-3.0661555 %) | Approved | 27742486 |
DrugRepV_2720 | Tenofovir disoproxil Fumarate | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-3.295385 %) | Approved, Investigational | 27742486 |
DrugRepV_2721 | Adefovir dipivoxil | Antiinfectives For Systemic Use | Hepatitis B virus | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-3.3056399 %) | Approved | 27742486 |
DrugRepV_2727 | Ofloxacin | Antiinfectives For Systemic Use | Respiratory tract infections | Kidney infection | Skin infection | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-3.4146475 %) | Approved | 27742486 |
DrugRepV_2731 | Rifabutin | Antiinfectives For Systemic Use | Mycobacterium avium complex (MAC) disease in patients with advanced Acquired immunodeficiency syndrome infection | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-3.4674544 %) | Approved, Investigational | 27742486 |
DrugRepV_2734 | Sulbactam | Antiinfectives For Systemic Use | Bacterial infections (Skin infection) | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-3.5031618 %) | Approved | 27742486 |
DrugRepV_2737 | Didanosine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-3.5849038 %) | Approved | 27742486 |
DrugRepV_2743 | Oxytetracycline | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-3.6733944 %) | Approved, Investigational, Vet approved | 27742486 |
DrugRepV_2764 | Zalcitabine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome/AIDS | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-4.2270809 %) | Approved | 27742486 |
DrugRepV_2775 | Flucytosine | Antiinfectives For Systemic Use | Fungal infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-4.4557163 %) | Approved, Investigational | 27742486 |
DrugRepV_2777 | Sulfamerazine | Antiinfectives For Systemic Use | Bacterial infections (Bronchitis, prostatitis and urinary tract infections) | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-4.4815833 %) | Approved, Vet approved | 27742486 |
DrugRepV_2783 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-4.5754617 %) | Approved | 27742486 |
DrugRepV_2791 | Abacavir Sulfate | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-4.7456882 %) | Approved | 27742486 |
DrugRepV_2795 | Roxithromycin | Antiinfectives For Systemic Use | Respiratory tract | Urinary and soft tissue infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-4.8220241 %) | Approved | 27742486 |
DrugRepV_2801 | Lamivudine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Hepatitis B virus | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-5.0142414 %) | Approved | 27742486 |
DrugRepV_2833 | Etravirine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-5.947872 %) | Approved | 27742486 |
DrugRepV_2839 | Emtricitabine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-6.2439742 %) | Approved | 27742486 |
DrugRepV_2849 | Amikacin Sulfate | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-6.6506378 %) | Approved | 27742486 |
DrugRepV_2851 | Sulfamethoxazole | Antiinfectives For Systemic Use | Bacterial infections (Bronchitis, prostatitis and urinary tract infections) | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-6.7837639 %) | Approved | 27742486 |
DrugRepV_2886 | Stavudine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-8.4649195 %) | Approved, Investigational | 27742486 |
DrugRepV_2892 | Sparfloxacin | Antiinfectives For Systemic Use | Pneumonia | Acute bacterial exacerbations of chronic bronchitis | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-8.7240967 %) | Approved, Investigational, Withdrawn | 27742486 |
DrugRepV_2901 | Amoxicillin | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-9.1354562 %) | Approved | 27742486 |
DrugRepV_2902 | Cefdinir | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-9.1747501 %) | Approved | 27742486 |
DrugRepV_2911 | Sulfanilamide | Antiinfectives For Systemic Use | Vulvovaginitis | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-9.7841731 %) | Approved | 27742486 |
DrugRepV_2922 | Amphotericin B | Antiinfectives For Systemic Use | Fungal infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-11.133117 %) | Approved | 27742486 |
DrugRepV_2933 | Erythromycin | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-14.433754 %) | Approved | 27742486 |
DrugRepV_2934 | Chloramphenicol | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | vAc-CHIKV 26S-Rhir-E | NA | Fusion index-Fluorescent Intensities | Increase (-14.926902 %) | Approved | 27742486 |
DrugRepV_2952 | Tetracycline | Antiinfectives For Systemic Use | Bacterial infections (Rocky Mountain spotted fever | Typhus fever | Tick fevers | Q fever | Rickettsialpox | Brill-Zinsser disease) | Chikungunya virus | Clinical isolate of CHIKV (East/Central/South African genotype) | NA | Plaque assay | Decrease (2.76 ÌÑ 107 pfu/ml) | Approved | 25970853 |
DrugRepV_2953 | Doxycycline | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | Clinical isolate of CHIKV (East/Central/South African genotype) | NA | Plaque assay | Decrease (1.50 ÌÑ 107 pfu/ml) | Approved | 25970853 |
DrugRepV_2954 | Rolitetracycline | Antiinfectives For Systemic Use | Bacterial infection | Chikungunya virus | Clinical isolate of CHIKV (East/Central/South African genotype) | NA | Plaque assay | Decrease (3.76 ÌÑ 107 pfu/ml) | Approved | 25970853 |
DrugRepV_2955 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Chikungunya virus | Clinical isolate of CHIKV (East/Central/South African genotype) | NA | Plaque assay | Decrease (0.96 ÌÑ 107 pfu/ml) | Approved | 25970853 |
DrugRepV_2956 | Aciclovir | Antiinfectives For Systemic Use | Viral infection | Chikungunya virus | Clinical isolate of CHIKV (East/Central/South African genotype) | NA | Plaque assay | Decrease (2.30 ÌÑ 107 pfu/ml) | Approved | 25970853 |
DrugRepV_2957 | Doxycycline | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | Clinical isolate of CHIKV (East/Central/South African genotype) | NA | NA | NA | Approved | 25970853 |
DrugRepV_2958 | Doxycycline | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | Clinical isolate of CHIKV (East/Central/South African genotype) | NA | NA | NA | Approved | 25970853 |
DrugRepV_2959 | Doxycycline | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | Clinical isolate of CHIKV (East/Central/South African genotype) | NA | Enzyme-linked immunosorbent assay | Decrease (50 %) | Approved | 25970853 |
DrugRepV_2960 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Chikungunya virus | Clinical isolate of CHIKV (East/Central/South African genotype) | NA | Enzyme-linked immunosorbent assay | Decrease (50 %) | Approved | 25970853 |
DrugRepV_2962 | Doxycycline | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | Clinical isolate of CHIKV (East/Central/South African genotype) | NA | Enzyme-linked immunosorbent assay | Decrease (51 %) | Approved | 25970853 |
DrugRepV_2963 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Chikungunya virus | Clinical isolate of CHIKV (East/Central/South African genotype) | NA | Enzyme-linked immunosorbent assay | Decrease (68 %) | Approved | 25970853 |
DrugRepV_2965 | Doxycycline | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | Clinical isolate of CHIKV (East/Central/South African genotype) | NA | Plaque assay | Decrease (68 %) | Approved | 25970853 |
DrugRepV_2966 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Chikungunya virus | Clinical isolate of CHIKV (East/Central/South African genotype) | NA | Plaque assay | Decrease (45 %) | Approved | 25970853 |
DrugRepV_2968 | Doxycycline | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | Clinical isolate of CHIKV (East/Central/South African genotype) | NA | Plaque assay | Decrease (71 %) | Approved | 25970853 |
DrugRepV_2969 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Chikungunya virus | Clinical isolate of CHIKV (East/Central/South African genotype) | NA | Plaque assay | Decrease (44 %) | Approved | 25970853 |
DrugRepV_2971 | Doxycycline | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | Clinical isolate of CHIKV (East/Central/South African genotype) | NA | Plaque assay | Decrease (43 %) | Approved | 25970853 |
DrugRepV_2972 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Chikungunya virus | Clinical isolate of CHIKV (East/Central/South African genotype) | NA | Plaque assay | Decrease (67 %) | Approved | 25970853 |
DrugRepV_2974 | Doxycycline | Antiinfectives For Systemic Use | Bacterial infections | Chikungunya virus | Clinical isolate of CHIKV (East/Central/South African genotype) | NA | MTT assay | Decrease (65 %) | Approved | 25970853 |
DrugRepV_2975 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Chikungunya virus | Clinical isolate of CHIKV (East/Central/South African genotype) | NA | MTT assay | Decrease (71.6 %) | Approved | 25970853 |
DrugRepV_2982 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Chikungunya virus | CHIKV replicon | NA | EGFP assay | Decrease (50 %) | Approved | 22205980 |
DrugRepV_2991 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Chikungunya virus | CHIKV replicon | NA | Rluc assay | Decrease (50 %) | Approved | 22205980 |
DrugRepV_3051 | Amphotericin B | Antiinfectives For Systemic Use | Fungal infection | Chikungunya virus | CHIKV-Rluc | NA | Luciferase reporter assay | Decrease (77 %) | Approved | 26752081 |
DrugRepV_3060 | Efavirenz | Antiinfectives For Systemic Use | Acquired immuno deficiency syndrome | Chikungunya virus | CHIKV-Rluc | NA | Luciferase reporter assay | Decrease (10 %) | Approved | 26752081 |
DrugRepV_3062 | Amphotericin B | Antiinfectives For Systemic Use | Fungal infection | Chikungunya virus | CHIKV-Rluc | NA | Renilla luciferase assay | No significant effect (90 %) | Approved | 26752081 |
DrugRepV_3156 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Chikungunya virus | Ross C347 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 14670584 |
DrugRepV_3164 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Chikungunya virus | Ross C347 | NA | Cytopathic effect (CPE) assay | Decrease (1.8 Log) | Approved | 14670584 |
DrugRepV_3168 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Chikungunya virus | Ross C347 | NA | Cytopathic effect (CPE) assay | Decrease (99 %) | Approved | 14670584 |
DrugRepV_3190 | Rimantadine | Antiinfectives For Systemic Use | Influenza A virus | Influenza virus | A/Aichi/2/68 | | Plaque assay | Decrease (50 %) | Approved, Investigational | 22028179 |
DrugRepV_3193 | Rimantadine | Antiinfectives For Systemic Use | Influenza A virus | Influenza virus | A/Aichi/2/68 | | Plaque assay | No significant reduction (No significant reduction log) | Approved, Investigational | 22028179 |
DrugRepV_3196 | Rimantadine | Antiinfectives For Systemic Use | Influenza A virus | Influenza virus | A/Aichi/2/68 | | Quantal assay | Decrease (1 log) | Approved, Investigational | 22028179 |
DrugRepV_3349 | Oseltamivir | Antiinfectives For Systemic Use | Influenza A/B virus | Influenza virus | WSN/H1N1 | | Plaque assay | No significant effect (40 %) | Approved | 29990517 |
DrugRepV_3351 | Oseltamivir | Antiinfectives For Systemic Use | Influenza A/B virus | Influenza virus | WSN/H1N1 | | Plaque assay | Decrease (1.5 Log) | Approved | 29990517 |
DrugRepV_3370 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Influenza virus | A/ WSN/1933 (H1N1) | | High-throughput screening | Decrease (50 %) | Approved | 24096239 |
DrugRepV_3377 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Middle East respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (50 %) | Approved | 24096239 |
DrugRepV_3384 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Middle East respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (90 %) | Approved | 24096239 |
DrugRepV_3390 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Middle East respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (99 %) | Approved | 24096239 |
DrugRepV_3396 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Middle East respiratory syndrome coronavirus | NA | NA | Real-time PCR | Decrease (>2 Log) | Approved | 24096239 |
DrugRepV_3402 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Middle East respiratory syndrome coronavirus | NA | NA | Plaque assay | Decrease (100 %) | Approved | 24096239 |
DrugRepV_3410 | Etravirine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Influenza virus | A/California/07/2009 (H1N1) | | Plaque assay | Decrease (50 %) | Approved | 28778830 |
DrugRepV_3411 | Rilpivirine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Influenza virus | A/California/07/2009 (H1N1) | | Plaque assay | Decrease (50 %) | Approved | 28778830 |
DrugRepV_3412 | Oseltamivir | Antiinfectives For Systemic Use | Influenza A/B virus | Influenza virus | A/California/07/2009 (H1N1) | | Plaque assay | Decrease (50 %) | Approved | 28778830 |
DrugRepV_3414 | Etravirine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Influenza virus | B/Bris/60/2008 (Victoria) | | Plaque assay | Decrease (50 %) | Approved | 28778830 |
DrugRepV_3415 | Oseltamivir | Antiinfectives For Systemic Use | Influenza A/B virus | Influenza virus | B/Bris/60/2008 (Victoria) | | Plaque assay | Decrease (50 %) | Approved | 28778830 |
DrugRepV_3418 | Oseltamivir | Antiinfectives For Systemic Use | Influenza A/B virus | Influenza virus | A/California/7/2009 (H1N1) | | Plaque assay | Decrease (1.7 Log) | Approved | 28778830 |
DrugRepV_3419 | Oseltamivir | Antiinfectives For Systemic Use | Influenza A/B virus | Influenza virus | A/California/7/2009 (H1N1) | | Plaque assay | Decrease (2 Log) | Approved | 28778830 |
DrugRepV_3421 | Oseltamivir | Antiinfectives For Systemic Use | Influenza A/B virus | Influenza virus | A/WSN/1933 (H1N1) | | Plaque assay | Decrease (1.4 Log) | Approved | 28778830 |
DrugRepV_3550 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Chikungunya virus | Asian strain | NA | Real-time PCR | Decrease (50 %) | Approved | 30455237 |
DrugRepV_3551 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Chikungunya virus | Asian strain | NA | Yield reduction assay | Decrease (50 %) | Approved | 30455237 |
DrugRepV_3552 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Chikungunya virus | Asian strain | NA | Real-time PCR | Decrease (50 %) | Approved | 30455237 |
DrugRepV_3553 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Chikungunya virus | Asian strain | NA | Yield reduction assay | Decrease (50 %) | Approved | 30455237 |
DrugRepV_3556 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Chikungunya virus | Asian strain | NA | Survival assay | Increase | Approved | 30455237 |
DrugRepV_3557 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Chikungunya virus | 181/clone 25 | NA | Plaque assay | Decrease (50 %) | Approved | 30354193 |
DrugRepV_3558 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Chikungunya virus | 181/clone 25 | NA | Plaque assay | Decrease (50 %) | Approved | 30354193 |
DrugRepV_3559 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Chikungunya virus | 181/clone 25 | NA | Plaque assay | Decrease (50 %) | Approved | 30354193 |
DrugRepV_3614 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Nipah virus | NA | NA | RT-PCR | Decrease | Approved | 16641448 |
DrugRepV_3620 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Nipah virus | NA | NA | RT-PCR | Decrease | Approved | 16641448 |
DrugRepV_3622 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Nipah virus | NA | NA | RT-PCR | Decrease | Approved | 16641448 |
DrugRepV_3697 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Marburg virus | NA | NA | Luciferase assay | Decrease (50 %) | Approved | 24713118 |
DrugRepV_3700 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Ebola virus | NA | NA | Luciferase assay | Decrease (50 %) | Approved | 24713118 |
DrugRepV_3703 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Marburg virus | NA | NA | NA | Decrease (83 %) | Approved | 24713118 |
DrugRepV_3707 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Ebola virus | NA | NA | NA | Decrease (0 %) | Approved | 24713118 |
DrugRepV_3875 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | Puerto Rican PRVABC-59 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 27838352 |
DrugRepV_3876 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | Puerto Rican PRVABC-59 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 27838352 |
DrugRepV_3877 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | Puerto Rican PRVABC-59 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 27838352 |
DrugRepV_3878 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | Malaysian P 6-740 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 27838352 |
DrugRepV_3879 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | Malaysian P 6-740 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 27838352 |
DrugRepV_3880 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | Ugandan MR-766 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 27838352 |
DrugRepV_3881 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | Ugandan MR-766 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 27838352 |
DrugRepV_3882 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | Ugandan MR-766 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 27838352 |
DrugRepV_4301 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Chikungunya virus | NA | NA | NA | Decrease (50 %) | Approved | 27460167 |
DrugRepV_4310 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Ebola virus | Mayinga | NA | MTT assay | Decrease (50 %) | Approved | 9988190 |
DrugRepV_4313 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Ebola virus | Sudan (Boneface strain) | NA | Plaque reduction assay | Decrease (50 %) | Approved | 9988190 |
DrugRepV_4515 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Influenza virus | NA | | NA | Decrease (50 %) | Approved | 15200845 |
DrugRepV_4516 | Zanamivir | Antiinfectives For Systemic Use | Influenza virus | Influenza virus | NA | | NA | Decrease (50 %) | Approved | 15200845 |
DrugRepV_4517 | Oseltamivir | Antiinfectives For Systemic Use | Influenza A/B virus | Influenza virus | NA | | NA | Decrease (50 %) | Approved | 15200845 |
DrugRepV_4529 | Ganciclovir | Antiinfectives For Systemic Use | Cytomegalovirus infection | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease | Approved, Investigational | 15200845 |
DrugRepV_4530 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease (100 %) | Approved | 15200845 |
DrugRepV_4531 | Indinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease | Approved | 15200845 |
DrugRepV_4532 | Nelfinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease | Approved | 15200845 |
DrugRepV_4533 | Saquinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease | Approved, Investigational | 15200845 |
DrugRepV_4534 | Lamivudine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Hepatitis B virus | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease | Approved | 15200845 |
DrugRepV_4535 | Zidovudine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome/AIDS | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease | Approved | 15200845 |
DrugRepV_4536 | Oseltamivir | Antiinfectives For Systemic Use | Influenza A/B virus | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease | Approved | 15200845 |
DrugRepV_4537 | Zanamivir | Antiinfectives For Systemic Use | Influenza virus | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease | Approved | 15200845 |
DrugRepV_4539 | Foscarnet | Antiinfectives For Systemic Use | Cytomegalovirus retinitis | Herpesviruses | Acquired immunodeficiency syndrome | Severe acute respiratory syndrome coronavirus | NA | NA | CPE inhibition assay | Decrease | Approved | 15200845 |
DrugRepV_4544 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | Approved | 15961169 |
DrugRepV_4545 | AZT | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | Approved | 15961169 |
DrugRepV_4546 | Lopinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Severe acute respiratory syndrome coronavirus | NA | NA | NA | Decrease (50 %) | Approved | 15961169 |
DrugRepV_4614 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Severe acute respiratory syndrome coronavirus | v2163 | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 19853271 |
DrugRepV_4615 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Severe acute respiratory syndrome coronavirus | Urbani | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 19853271 |
DrugRepV_4630 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Severe acute respiratory syndrome coronavirus | v2163 | NA | Survival assay | No significant effect | Approved | 19853271 |
DrugRepV_4648 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | NA | NA | Plaque assay | Decrease (50 %) | Approved | 28098253 |
DrugRepV_4649 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | NA | NA | Plaque assay | Decrease (50 %) | Approved | 28098253 |
DrugRepV_4651 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | NA | NA | Plaque assay | Decrease (1.00E+02 pfu/ml) | Approved | 28098253 |
DrugRepV_4652 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | NA | NA | Plaque assay | Decrease (5.00E+07 pfu/ml) | Approved | 28098253 |
DrugRepV_4688 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | NA | NA | Phenotypic assay | Decrease (50 %) | Approved | 30061280 |
DrugRepV_4692 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Zika virus | NA | NA | Phenotypic assay | Decrease (50 %) | Approved | 30061280 |
DrugRepV_4709 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | NA | NA | Immunoflourescence assay | Decrease | Approved | 30061280 |
DrugRepV_4778 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Middle East respiratory syndrome coronavirus | Hu/Jordan-N3/2012 | NA | Virus yield reduction assay | Decrease (30 %) | Approved | 24323636 |
DrugRepV_4822 | Teicoplanin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | NA | NA | Luciferase assay | Decrease (50 %) | Approved | 26953343 |
DrugRepV_4823 | Teicoplanin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | NA | NA | Luciferase assay | Decrease (50 %) | Approved | 26953343 |
DrugRepV_4824 | Dalbavancin | Antiinfectives For Systemic Use | Bacterial infections | Ebola virus | NA | NA | Luciferase assay | Decrease (50 %) | Approved | 26953343 |
DrugRepV_4825 | Oritavancin | Antiinfectives For Systemic Use | Acute bacterial skin | Skin structure infections | Ebola virus | NA | NA | Luciferase assay | Decrease (50 %) | Approved | 26953343 |
DrugRepV_4826 | Telavancin | Antiinfectives For Systemic Use | Skin infections (Bacterial) | Ebola virus | NA | NA | Luciferase assay | Decrease (50 %) | Approved | 26953343 |
DrugRepV_4829 | Teicoplanin | Antiinfectives For Systemic Use | Bacterial infections | Middle East respiratory syndrome coronavirus | NA | NA | Luciferase assay | Decrease (50 %) | Approved | 26953343 |
DrugRepV_4830 | Dalbavancin | Antiinfectives For Systemic Use | Bacterial infections | Middle East respiratory syndrome coronavirus | NA | NA | Luciferase assay | Decrease (50 %) | Approved | 26953343 |
DrugRepV_4831 | Oritavancin | Antiinfectives For Systemic Use | Acute bacterial skin | Skin structure infections | Middle East respiratory syndrome coronavirus | NA | NA | Luciferase assay | Decrease (50 %) | Approved | 26953343 |
DrugRepV_4832 | Telavancin | Antiinfectives For Systemic Use | Skin infections (Bacterial) | Middle East respiratory syndrome coronavirus | NA | NA | Luciferase assay | Decrease (50 %) | Approved | 26953343 |
DrugRepV_5078 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Crimean-Congo hemorrhagic fever virus | 10200 | NA | Survival assay | No significant effect | Approved | 29936152 |
DrugRepV_5079 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Crimean-Congo hemorrhagic fever virus | Hoti | NA | Survival assay | No significant effect | Approved | 29936152 |
DrugRepV_5080 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Crimean-Congo hemorrhagic fever virus | 10200 | NA | Real-time PCR | Decrease | Approved | 29936152 |
DrugRepV_5081 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Crimean-Congo hemorrhagic fever virus | Hoti | NA | Real-time PCR | Decrease | Approved | 29936152 |
DrugRepV_5082 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Crimean-Congo hemorrhagic fever virus | NA | NA | Real-time PCR | Decrease (100 Copies/ml) | Approved | 29584885 |
DrugRepV_5098 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | Decrease (50 %) | Approved | 29024765 |
DrugRepV_5120 | ABT-333 | Antiinfectives For Systemic Use | Hepatitis C virus | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | No significant effect (39 %) | Approved | 29024765 |
DrugRepV_5125 | Lamivudine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Hepatitis B virus | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | No significant effect (24 %) | Approved | 29024765 |
DrugRepV_5132 | PSI-7977 | Antiinfectives For Systemic Use | Hepatitis C virus | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | No significant effect (4 %) | Approved | 29024765 |
DrugRepV_5136 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | No significant effect (2 %) | Approved | 29024765 |
DrugRepV_5137 | Stavudine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | No significant effect (26 %) | Approved, Investigational | 29024765 |
DrugRepV_5139 | Tenofovir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | No significant effect (0 %) | Approved, Investigational | 29024765 |
DrugRepV_5140 | Zidovudine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome/AIDS | Crimean-Congo hemorrhagic fever virus | CCHFV/ZsG | NA | Fluorescence-based assay | No significant effect (27 %) | Approved | 29024765 |
DrugRepV_5184 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Rift Valley fever virus | ZH501 | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 25144302 |
DrugRepV_5190 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Rift Valley fever virus | ZH501 | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 25144302 |
DrugRepV_5196 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Ebola virus | Zaire | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 25144302 |
DrugRepV_5201 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Marburg virus | Ci67 | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 25144302 |
DrugRepV_5205 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Lassa virus | Josiah | NA | Immunoflourescence assay | Decrease (50 %) | Approved | 25144302 |
DrugRepV_5219 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Rift Valley fever virus | RVF-VLPs | NA | RLuc expression | Decrease (87.2 %) | Approved | 21994655 |
DrugRepV_5225 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Crimean-Congo hemorrhagic fever virus | IbAr 10200 | NA | Neutral red uptake assay | Decrease (50 %) | Approved | 15026198 |
DrugRepV_5230 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Crimean-Congo hemorrhagic fever virus | Spu 128/81 | NA | Neutral red uptake assay | Decrease (50 %) | Approved | 15026198 |
DrugRepV_5235 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Crimean-Congo hemorrhagic fever virus | Hy-13 | NA | Neutral red uptake assay | Decrease (50 %) | Approved | 15026198 |
DrugRepV_5240 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Crimean-Congo hemorrhagic fever virus | UG3010 | NA | Neutral red uptake assay | Decrease (50 %) | Approved | 15026198 |
DrugRepV_5252 | Rifampicin | Antiinfectives For Systemic Use | Tuberculosis and Tuberculosis-related mycobacterial infections | Variola virus | Butler | NA | Plaque assay | Decrease (Complete inhibition Plaque size) | Approved | 4321450 |
DrugRepV_5475 | Penciclovir | Antiinfectives For Systemic Use | Recurrent cold sores on the lips and face from Herpesvirus invections | SARS Coronavirus-2 | nCoV- 2019BetaCoV/Wuhan/WIV04/2019 | NA | qRT-PCR | Decrease (50 %) | Approved | 32020029 |
DrugRepV_5524 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Lassa virus | NA | NA | Gaussia luciferase (Gluc) Glow assay | Decrease (50 %) | Approved | 31786250 |
DrugRepV_5551 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | Approved | 32353859 |
DrugRepV_5591 | Chloramphenicol | Antiinfectives For Systemic Use | Bacterial infections | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | Approved | 32353859 |
DrugRepV_5592 | Tigecycline | Antiinfectives For Systemic Use | Complicated skin and skin structure infections | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | Approved | 32353859 |
DrugRepV_5593 | Linezolid | Antiinfectives For Systemic Use | Bacterial infections | SARS Coronavirus-2 | 2019-nCoV/USA-WA1/2020 | NA | NA | Decrease (50 %) | Approved, Investigational | 32353859 |
DrugRepV_5628 | Minocycline | Antiinfectives For Systemic Use | Rocky Mountain spotted fever | Typhus fever and the typhus group | Q fever | Rickettsial pox | tick fevers caused by Rickettsiae | Upper respiratory tract infections caused by Streptococcus pneumoniae | Dengue virus | 16681 | | Enzyme-linked immunosorbent assay | Decrease (20 %) | Approved, Investigational | 27396621 |
DrugRepV_5629 | Minocycline | Antiinfectives For Systemic Use | Rocky Mountain spotted fever | Typhus fever and the typhus group | Q fever | Rickettsial pox | tick fevers caused by Rickettsiae | Upper respiratory tract infections caused by Streptococcus pneumoniae | Dengue virus | Hawaii | | Enzyme-linked immunosorbent assay | Decrease (20 %) | Approved, Investigational | 27396621 |
DrugRepV_5630 | Minocycline | Antiinfectives For Systemic Use | Rocky Mountain spotted fever | Typhus fever and the typhus group | Q fever | Rickettsial pox | tick fevers caused by Rickettsiae | Upper respiratory tract infections caused by Streptococcus pneumoniae | Dengue virus | H87 | | Enzyme-linked immunosorbent assay | Decrease (30 %) | Approved, Investigational | 27396621 |
DrugRepV_5631 | Minocycline | Antiinfectives For Systemic Use | Rocky Mountain spotted fever | Typhus fever and the typhus group | Q fever | Rickettsial pox | tick fevers caused by Rickettsiae | Upper respiratory tract infections caused by Streptococcus pneumoniae | Dengue virus | H241 | | Enzyme-linked immunosorbent assay | Decrease (30 %) | Approved, Investigational | 27396621 |
DrugRepV_5632 | Minocycline | Antiinfectives For Systemic Use | Rocky Mountain spotted fever | Typhus fever and the typhus group | Q fever | Rickettsial pox | tick fevers caused by Rickettsiae | Upper respiratory tract infections caused by Streptococcus pneumoniae | Dengue virus | 16681 | | Real-time PCR | Decrease (50 %) | Approved, Investigational | 27396621 |
DrugRepV_5633 | Minocycline | Antiinfectives For Systemic Use | Rocky Mountain spotted fever | Typhus fever and the typhus group | Q fever | Rickettsial pox | tick fevers caused by Rickettsiae | Upper respiratory tract infections caused by Streptococcus pneumoniae | Dengue virus | 16681 | | Focus forming assay | Decrease (1 Log10 (FFU/ml)) | Approved, Investigational | 27396621 |
DrugRepV_5634 | Lomefloxacin | Antiinfectives For Systemic Use | Bacterial infections (respiratory tract (chronic bronchitis) and urinary tract) | Dengue virus | 16681 | | Enzyme-linked immunosorbent assay | No significant effect (5 %) | Approved, Investigational | 27396621 |
DrugRepV_5635 | Netilmicin | Antiinfectives For Systemic Use | Bacteremia | Septicaemia | Respiratory tract infections | Skin and soft-tissue infection | Burns | Wounds | Peri-operative infections caused by susceptible strains | Dengue virus | 16681 | | Enzyme-linked immunosorbent assay | No significant effect (0 %) | Approved, Investigational | 27396621 |
DrugRepV_5713 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Dengue virus | New Guinea C | | Fluorescence-based assay | Decrease (50 %) | Approved | 20973722 |
DrugRepV_5723 | Acetylspiramycin | Antiinfectives For Systemic Use | Microbial infections | Dengue virus | New Guinea C | | Fluorescence-based assay | Decrease (50 %) | NA | 20973722 |
DrugRepV_5743 | Telaprevir | Antiinfectives For Systemic Use | Hepatitis C virus | Dengue virus | DV2-NGC | | Plaque assay | Decrease (50 %) | Approved | 29297305 |
DrugRepV_5744 | Asunaprevir | Antiinfectives For Systemic Use | Hepatitis C virus | Dengue virus | DV2-NGC | | Plaque assay | Decrease (50 %) | Phase III | 29297305 |
DrugRepV_5745 | Boceprevir | Antiinfectives For Systemic Use | Hepatitis C virus | Dengue virus | DV2-NGC | | Real-time PCR | No significant effect | Phase II | 29297305 |
DrugRepV_5746 | Telaprevir | Antiinfectives For Systemic Use | Hepatitis C virus | Dengue virus | DV2-NGC | | Real-time PCR | Decrease (2 Logs) | Approved | 29297305 |
DrugRepV_5747 | Asunaprevir | Antiinfectives For Systemic Use | Hepatitis C virus | Dengue virus | DV2-NGC | | Real-time PCR | Decrease (5 Logs) | Phase III | 29297305 |
DrugRepV_5752 | Nelfinavir Mesylate | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Dengue virus | DENV-2 replicon | | Luciferase reporter assay | No significant effect (0 %) | NA | 28814523 |
DrugRepV_5779 | Clarithromycin | Antiinfectives For Systemic Use | NA | Dengue virus | Singapore isolates | | Plaque assay | Decrease (72 %) | NA | 25251726 |
DrugRepV_6128 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Dengue virus | New Guinea C | | NA | Decrease (50 %) | Approved | 29890736 |
DrugRepV_6138 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Dengue virus | New Guinea C | | DENV replicon assay | Decrease (50 %) | Approved | 29672522 |
DrugRepV_6159 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Dengue virus | 16681 | | MTT assay | Decrease (50 %) | Approved | 22068705 |
DrugRepV_6168 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Dengue virus | 02--20 | | Luciferase assay | Decrease (50 %) | Approved | 24858611 |
DrugRepV_6178 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Dengue virus | ThNH-7/93 | | Fluorescent focus-forming assay | Decrease (50 %) | Approved | 22784856 |
DrugRepV_6182 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Dengue virus | New Guinea C (NGC) | | Cell proliferation assay | Decrease (50 %) | Approved | 17662475 |
DrugRepV_6215 | Tetracycline | Antiinfectives For Systemic Use | Bacterial infections (Rocky Mountain spotted fever | Typhus fever | Tick fevers | Q fever | Rickettsialpox | Brill-Zinsser disease) | Dengue virus | NA | | Virus inhibition assay | Decrease (23.6 ± 2.1 %) | Approved | 24522138 |
DrugRepV_6216 | Oxytetracycline | Antiinfectives For Systemic Use | Bacterial infections | Dengue virus | NA | | Virus inhibition assay | Decrease (18.8 ± 2.1 %) | Approved, Investigational, Vet approved | 24522138 |
DrugRepV_6217 | Doxycycline | Antiinfectives For Systemic Use | Bacterial infections | Dengue virus | NA | | Virus inhibition assay | Decrease (50 %) | Approved | 24522138 |
DrugRepV_6218 | Rolitetracycline | Antiinfectives For Systemic Use | Bacterial infection | Dengue virus | NA | | Virus inhibition assay | Decrease (32.8 ± 2.6 %) | Approved | 24522138 |
DrugRepV_6219 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Dengue virus | NA | | Virus inhibition assay | Decrease (50 %) | Approved | 24522138 |
DrugRepV_6226 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Dengue virus | 16681 | | Plaque assay | Decrease (1.75 * 105 pfu/ml) | Approved | 7201778 |
DrugRepV_6348 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Dengue virus | New Guinea C (NGC) | | NA | Decrease (50 %) | Approved | 26856827 |
DrugRepV_6491 | Lamivudine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Hepatitis B virus | Human immunodeficiency virus | NA | | Modelling based approach | Decrease (50 %) | Approved | 26796142 |
DrugRepV_6492 | Emtricitabine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | NA | | Modelling based approach | Decrease (50 %) | Approved | 26796142 |
DrugRepV_6493 | Tenofovir disoproxil Fumarate | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | NA | | Modelling based approach | Decrease (50 %) | NA | 26796142 |
DrugRepV_6501 | Minocycline | Antiinfectives For Systemic Use | Rocky Mountain spotted fever | Typhus fever and the typhus group | Q fever | Rickettsial pox | tick fevers caused by Rickettsiae | Upper respiratory tract infections caused by Streptococcus pneumoniae | Human immunodeficiency virus | HIV-1ADA | | Enzyme-linked immunosorbent assay | Decrease (50 %) | Approved, Investigational | 15385252 |
DrugRepV_6502 | Minocycline | Antiinfectives For Systemic Use | Rocky Mountain spotted fever | Typhus fever and the typhus group | Q fever | Rickettsial pox | tick fevers caused by Rickettsiae | Upper respiratory tract infections caused by Streptococcus pneumoniae | Human immunodeficiency virus | HIV-1ADA | | Enzyme-linked immunosorbent assay | Decrease (71-96 %) | Approved, Investigational | 15385252 |
DrugRepV_6503 | Minocycline | Antiinfectives For Systemic Use | Rocky Mountain spotted fever | Typhus fever and the typhus group | Q fever | Rickettsial pox | tick fevers caused by Rickettsiae | Upper respiratory tract infections caused by Streptococcus pneumoniae | Human immunodeficiency virus | HIV-1ADA | | Enzyme-linked immunosorbent assay | Decrease (85 %) | Approved, Investigational | 15385252 |
DrugRepV_6504 | Minocycline | Antiinfectives For Systemic Use | Rocky Mountain spotted fever | Typhus fever and the typhus group | Q fever | Rickettsial pox | tick fevers caused by Rickettsiae | Upper respiratory tract infections caused by Streptococcus pneumoniae | Human immunodeficiency virus | HIV-1BaL | | Enzyme-linked immunosorbent assay | Decrease (65 %) | Approved, Investigational | 15385252 |
DrugRepV_6505 | Minocycline | Antiinfectives For Systemic Use | Rocky Mountain spotted fever | Typhus fever and the typhus group | Q fever | Rickettsial pox | tick fevers caused by Rickettsiae | Upper respiratory tract infections caused by Streptococcus pneumoniae | Human immunodeficiency virus | HIV-189.6 | | Enzyme-linked immunosorbent assay | Decrease (NA %) | Approved, Investigational | 15385252 |
DrugRepV_6506 | Minocycline | Antiinfectives For Systemic Use | Rocky Mountain spotted fever | Typhus fever and the typhus group | Q fever | Rickettsial pox | tick fevers caused by Rickettsiae | Upper respiratory tract infections caused by Streptococcus pneumoniae | Human immunodeficiency virus | HIV-1JR-FL env | | Luciferase reporter assay | Decrease (80 %) | Approved, Investigational | 15385252 |
DrugRepV_6507 | Minocycline | Antiinfectives For Systemic Use | Rocky Mountain spotted fever | Typhus fever and the typhus group | Q fever | Rickettsial pox | tick fevers caused by Rickettsiae | Upper respiratory tract infections caused by Streptococcus pneumoniae | Human immunodeficiency virus | HIV-1 VSV-G env | | Luciferase reporter assay | Decrease (60 %) | Approved, Investigational | 15385252 |
DrugRepV_6508 | Minocycline | Antiinfectives For Systemic Use | Rocky Mountain spotted fever | Typhus fever and the typhus group | Q fever | Rickettsial pox | tick fevers caused by Rickettsiae | Upper respiratory tract infections caused by Streptococcus pneumoniae | Human immunodeficiency virus | HIV-1 AML-V env | | Luciferase reporter assay | No significant effect (40 %) | Approved, Investigational | 15385252 |
DrugRepV_6509 | Minocycline | Antiinfectives For Systemic Use | Rocky Mountain spotted fever | Typhus fever and the typhus group | Q fever | Rickettsial pox | tick fevers caused by Rickettsiae | Upper respiratory tract infections caused by Streptococcus pneumoniae | Human immunodeficiency virus | HIV-1 VSV-G env | | Luciferase reporter assay | Decrease (50 %) | Approved, Investigational | 15385252 |
DrugRepV_6511 | Efavirenz | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Wild type | | ECL RT biochemical assay | Decrease (50 %) | NA | 24379202 |
DrugRepV_6512 | Etravirine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Wild type | | ECL RT biochemical assay | Decrease (50 %) | NA | 24379202 |
DrugRepV_6513 | Rilpivirine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Wild type | | ECL RT biochemical assay | Decrease (50 %) | Approved | 24379202 |
DrugRepV_6515 | Efavirenz | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | K103N | | ECL RT biochemical assay | Decrease (50 %) | NA | 24379202 |
DrugRepV_6516 | Etravirine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | K103N | | ECL RT biochemical assay | Decrease (50 %) | NA | 24379202 |
DrugRepV_6517 | Rilpivirine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | K103N | | ECL RT biochemical assay | Decrease (50 %) | Approved | 24379202 |
DrugRepV_6519 | Efavirenz | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Y181C | | ECL RT biochemical assay | Decrease (50 %) | NA | 24379202 |
DrugRepV_6520 | Etravirine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Y181C | | ECL RT biochemical assay | Decrease (50 %) | NA | 24379202 |
DrugRepV_6521 | Rilpivirine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Y181C | | ECL RT biochemical assay | Decrease (50 %) | Approved | 24379202 |
DrugRepV_6523 | Efavirenz | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Wild type | | HIV multiple-cycle replication assay | Decrease (95 %) | NA | 24379202 |
DrugRepV_6524 | Etravirine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Wild type | | HIV multiple-cycle replication assay | Decrease (95 %) | NA | 24379202 |
DrugRepV_6525 | Rilpivirine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Wild type | | HIV multiple-cycle replication assay | Decrease (95 %) | Approved | 24379202 |
DrugRepV_6527 | Efavirenz | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | K103N | | HIV multiple-cycle replication assay | Decrease (95 %) | NA | 24379202 |
DrugRepV_6528 | Etravirine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | K103N | | HIV multiple-cycle replication assay | Decrease (95 %) | NA | 24379202 |
DrugRepV_6529 | Rilpivirine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | K103N | | HIV multiple-cycle replication assay | Decrease (95 %) | Approved | 24379202 |
DrugRepV_6531 | Efavirenz | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Y181C | | HIV multiple-cycle replication assay | Decrease (95 %) | NA | 24379202 |
DrugRepV_6532 | Etravirine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Y181C | | HIV multiple-cycle replication assay | Decrease (95 %) | NA | 24379202 |
DrugRepV_6533 | Rilpivirine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Y181C | | HIV multiple-cycle replication assay | Decrease (95 %) | Approved | 24379202 |
DrugRepV_6535 | Efavirenz | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | K103N/Y181C | | HIV multiple-cycle replication assay | Decrease (95 %) | NA | 24379202 |
DrugRepV_6536 | Etravirine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | K103N/Y181C | | HIV multiple-cycle replication assay | Decrease (95 %) | NA | 24379202 |
DrugRepV_6537 | Rilpivirine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | K103N/Y181C | | HIV multiple-cycle replication assay | Decrease (95 %) | Approved | 24379202 |
DrugRepV_6568 | Saquinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | HIV-1ERS104pre | | p24 assay | Decrease (50 %) | Approved, Investigational | 20810732 |
DrugRepV_6569 | Amprenavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | HIV-1ERS104pre | | p24 assay | Decrease (50 %) | Approved | 20810732 |
DrugRepV_6570 | Indinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | HIV-1ERS104pre | | p24 assay | Decrease (50 %) | Approved | 20810732 |
DrugRepV_6571 | Nelfinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | HIV-1ERS104pre | | p24 assay | Decrease (50 %) | Approved | 20810732 |
DrugRepV_6572 | Ritonavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | HIV-1ERS104pre | | p24 assay | Decrease (50 %) | Approved, Investigational | 20810732 |
DrugRepV_6573 | Lopinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | HIV-1ERS104pre | | p24 assay | Decrease (50 %) | Approved | 20810732 |
DrugRepV_6574 | Atazanavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | HIV-1ERS104pre | | p24 assay | Decrease (50 %) | Approved | 20810732 |
DrugRepV_6575 | Tipranavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | HIV-1ERS104pre | | p24 assay | Decrease (50 %) | Approved, Investigational | 20810732 |
DrugRepV_6576 | Darunavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | HIV-1ERS104pre | | p24 assay | Decrease (50 %) | Approved | 20810732 |
DrugRepV_6577 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | WT | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6578 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Y143R (RAL) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6579 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | N155H(RAL) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6580 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Q148H (RAL) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6581 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T661(EVG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6582 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E92Q (EVG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6583 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | H51Y (DTG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6584 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G118R (DTG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6585 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | R263K (DTG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6586 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | H51Y/R263K (DTG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6587 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K/R263K (DTG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6588 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | WT | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6589 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Y143R (RAL) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6590 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | N155H(RAL) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6591 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Q148H (RAL) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6592 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T661(EVG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6593 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E92Q (EVG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6594 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | H51Y (DTG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6595 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G118R (DTG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6596 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | R263K (DTG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6597 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | H51Y/R263K (DTG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6598 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K/R263K (DTG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6599 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | WT | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6600 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Y143R (RAL) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6601 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | N155H(RAL) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6602 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Q148H (RAL) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6603 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T661(EVG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6604 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E92Q (EVG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6605 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | H51Y (DTG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6606 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G118R (DTG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6607 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | R263K (DTG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6608 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | H51Y/R263K (DTG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6609 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K/R263K (DTG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6621 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | WT | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6622 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Y143R (RAL) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6623 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | N155H(RAL) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6624 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Q148H (RAL) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6625 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T661(EVG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6626 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E92Q (EVG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6627 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | H51Y (DTG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6628 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G118R (DTG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6629 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | R263K (DTG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6630 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | H51Y/R263K (DTG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6631 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K/R263K (DTG) | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6632 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | M50I | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6633 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | L74M | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6634 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T97A | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6635 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | S119R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6636 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6637 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6638 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q146L | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6639 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q146P | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6640 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6641 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q148K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6642 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6643 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | S153Y | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6644 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | M50I | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6645 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | L74M | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6646 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T97A | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6647 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | S119R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6648 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6649 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6650 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q146L | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6651 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q146P | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6652 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6653 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q148K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6654 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6655 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | S153Y | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6656 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | M50I | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6657 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | L74M | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6658 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T97A | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6659 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | S119R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6660 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6661 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6662 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q146L | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6663 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q146P | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6664 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6665 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q148K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6666 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6667 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | S153Y | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6680 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | M50I | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6681 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | L74M | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6682 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T97A | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6683 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | S119R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6684 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6685 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6686 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q146L | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6687 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q146P | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6688 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6689 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q148K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6690 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6691 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | S153Y | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6692 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140A/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6693 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Y143R/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6694 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q148H/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6695 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K/Q148K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6696 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140A/Q148K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6697 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Q148K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6698 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138A/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6699 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6700 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140A/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6701 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140C/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6702 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6703 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q148R/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6704 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140A/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6705 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Y143R/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6706 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q148H/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6707 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K/Q148K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6708 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140A/Q148K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6709 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Q148K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6710 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138A/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6711 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6712 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140A/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6713 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140C/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6714 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6715 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q148R/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6716 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140A/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6717 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Y143R/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6718 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q148H/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6719 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K/Q148K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6720 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140A/Q148K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6721 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Q148K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6722 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138A/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6723 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6724 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140A/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6725 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140C/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6726 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6727 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q148R/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6740 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140A/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6741 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Y143R/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6742 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q148H/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6743 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K/Q148K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6744 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140A/Q148K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6745 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Q148K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6746 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138A/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6747 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6748 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140A/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6749 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140C/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6750 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6751 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Q148R/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6752 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T66I/E157Q | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6753 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E92Q/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6754 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6755 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Y143H/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6756 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Y143R/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6757 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | N155H/G163R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6758 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T66I/E157Q | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6759 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E92Q/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6760 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6761 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Y143H/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6762 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Y143R/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6763 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | N155H/G163R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6764 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T66I/E157Q | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6765 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E92Q/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6766 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6767 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Y143H/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6768 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Y143R/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6769 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | N155H/G163R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6776 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T66I/E157Q | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6777 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E92Q/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6778 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6779 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Y143H/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6780 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | Y143R/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6781 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | N155H/G163R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6782 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | 97A/Y143R/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6783 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T97A/Q148H/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6784 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K/G140A/Q148K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6785 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | L74M/G140A/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6786 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | L74M/G140C/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6787 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K/G140C/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6788 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138A/S147G/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6789 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | 97A/Y143R/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6790 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T97A/Q148H/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6791 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K/G140A/Q148K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6792 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | L74M/G140A/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6793 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | L74M/G140C/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6794 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K/G140C/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6795 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138A/S147G/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6796 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | 97A/Y143R/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6797 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T97A/Q148H/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6798 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K/G140A/Q148K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6799 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | L74M/G140A/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6800 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | L74M/G140C/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6801 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K/G140C/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6802 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138A/S147G/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6810 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | 97A/Y143R/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6811 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T97A/Q148H/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6812 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K/G140A/Q148K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6813 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | L74M/G140A/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6814 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | L74M/G140C/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6815 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K/G140C/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6816 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138A/S147G/Q148R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6817 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T66I/T97A/E157Q | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6818 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T97A/Y143R/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6819 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Y143R/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6820 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E92Q/N155H/G163R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6821 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T66I/T97A/E157Q | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6822 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T97A/Y143R/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6823 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Y143R/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6824 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E92Q/N155H/G163R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6825 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T66I/T97A/E157Q | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6826 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T97A/Y143R/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6827 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Y143R/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6828 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E92Q/N155H/G163R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6833 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T66I/T97A/E157Q | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6834 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T97A/Y143R/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6835 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Y143R/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6836 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E92Q/N155H/G163R | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6837 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T97A/G140S/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6838 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138A/G140S/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6839 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K/G140S/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6840 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Y143R/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6841 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Q148H/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6842 | Raltegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Q148H/G163K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6843 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T97A/G140S/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6844 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138A/G140S/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6845 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K/G140S/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6846 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Y143R/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6847 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Q148H/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6848 | Elvitegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Q148H/G163K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6849 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T97A/G140S/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6850 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138A/G140S/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6851 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K/G140S/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6852 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Y143R/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6853 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Q148H/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6854 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Q148H/G163K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6861 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | T97A/G140S/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6862 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138A/G140S/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6863 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | E138K/G140S/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6864 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Y143R/Q148H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6865 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Q148H/N155H | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6866 | Bictegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | G140S/Q148H/G163K | | Single-round viral replication assay | Decrease (50 %) | Approved | 29769116 |
DrugRepV_6926 | AzidoThymidine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | IIIB | | MTT assay | Decrease (50 %) | Approved | 25970561 |
DrugRepV_6956 | AzidoThymidine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | ROD | | MTT assay | Decrease (50 %) | Approved | 25970561 |
DrugRepV_6958 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | Approved | 15200845 |
DrugRepV_6959 | Lamivudine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Hepatitis B virus | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | Approved | 15200845 |
DrugRepV_6960 | Zidovudine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome/AIDS | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | Approved | 15200845 |
DrugRepV_6961 | Saquinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | Approved, Investigational | 15200845 |
DrugRepV_6962 | Nelfinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | NA | | NA | Decrease (95 %) | Approved | 15200845 |
DrugRepV_6963 | Indinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Human immunodeficiency virus | NA | | NA | Decrease (50 %) | Approved | 15200845 |
DrugRepV_7011 | Nelfinavir Mesylate | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Japanese encephalitis virus | AT31 | | Luciferase reporter assay | Decrease (50 %) | NA | 28814523 |
DrugRepV_7020 | Nelfinavir Mesylate | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Japanese encephalitis virus | AT31 | | Plaque assay | Decrease (3 Logs) | NA | 28814523 |
DrugRepV_7025 | Nelfinavir Mesylate | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Japanese encephalitis virus | AT31 | | Real-time PCR | Decrease (0.1 %) | NA | 28814523 |
DrugRepV_7030 | Nelfinavir Mesylate | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Japanese encephalitis virus | AT31 | | Immunoflourescence assay | Decrease (100 %) | NA | 28814523 |
DrugRepV_7035 | Nelfinavir Mesylate | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Japanese encephalitis virus | AT31 | | Luciferase reporter assay | Decrease (70 %) | NA | 28814523 |
DrugRepV_7040 | Nelfinavir Mesylate | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Japanese encephalitis virus | AT31 | | Luciferase reporter assay | Decrease (100 %) | NA | 28814523 |
DrugRepV_7045 | Nelfinavir Mesylate | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | West Nile virus | WNV replicon | | Luciferase reporter assay | Decrease (72 %) | NA | 28814523 |
DrugRepV_7089 | Teicoplanin | Antiinfectives For Systemic Use | Bacterial infections | Polio virus | Sabin | | Plaque assay | No significant effect | Approved | 26585243 |
DrugRepV_7447 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | West Nile virus | New York | | Visual assay | Decrease (50 %) | Approved | 12076755 |
DrugRepV_7448 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | West Nile virus | Uganda strain B 956 | | Visual assay | Decrease (50 %) | Approved | 12076755 |
DrugRepV_7459 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | West Nile virus | New York | | NR assay | Decrease (50 %) | Approved | 12076755 |
DrugRepV_7460 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | West Nile virus | Uganda strain B 956 | | NR assay | Decrease (50 %) | Approved | 12076755 |
DrugRepV_7506 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | West Nile virus | New York | | Visual assay | Decrease (50 %) | Approved | 12076755 |
DrugRepV_7511 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | West Nile virus | New York | | Virus yield reduction assay | Decrease (90 %) | Approved | 12076755 |
DrugRepV_7519 | Rifampicin | Antiinfectives For Systemic Use | Tuberculosis and Tuberculosis-related mycobacterial infections | Vaccinia virus | NA | | Plaque assay | Decrease (Complete inhibition Plaque size) | Approved | 4321450 |
DrugRepV_7525 | Telaprevir | Antiinfectives For Systemic Use | Hepatitis C virus | Enterovirus | US/KY/14-18953 | | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 30674624 |
DrugRepV_7526 | Telaprevir | Antiinfectives For Systemic Use | Hepatitis C virus | Enterovirus | US/MO/14-18949 | | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 30674624 |
DrugRepV_7527 | Telaprevir | Antiinfectives For Systemic Use | Hepatitis C virus | Enterovirus | US/MO/14-18947 | | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 30674624 |
DrugRepV_7528 | Telaprevir | Antiinfectives For Systemic Use | Hepatitis C virus | Enterovirus | US/IL/14-18952 | | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 30674624 |
DrugRepV_7529 | Telaprevir | Antiinfectives For Systemic Use | Hepatitis C virus | Enterovirus | US/IL/14-18956 | | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 30674624 |
DrugRepV_7530 | Telaprevir | Antiinfectives For Systemic Use | Hepatitis C virus | Enterovirus | US/KY/14-18953 | | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 30674624 |
DrugRepV_7531 | Telaprevir | Antiinfectives For Systemic Use | Hepatitis C virus | Enterovirus | US/KY/14-18953 | | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 30674624 |
DrugRepV_7532 | Telaprevir | Antiinfectives For Systemic Use | Hepatitis C virus | Enterovirus | US/KY/14-18953 | | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 30674624 |
DrugRepV_7533 | Telaprevir | Antiinfectives For Systemic Use | Hepatitis C virus | Enterovirus | US/KY/14-18953 | | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 30674624 |
DrugRepV_7550 | Nelfinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | NA | NA | RT-PCR | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7551 | Nelfinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | NA | NA | RT-PCR | Decrease (90 %) | Approved | 32438446 |
DrugRepV_7560 | Atazanavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | Brazil/RJ-314/2020 | NA | RT-PCR | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7561 | Atazanavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | Brazil/RJ-314/2020 | NA | RT-PCR | Decrease (90 %) | Approved | 32438446 |
DrugRepV_7562 | Azithromycin | Antiinfectives For Systemic Use | Microbial infections | SARS Coronavirus-2 | BavPat1 | NA | RT-PCR | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7563 | Azithromycin | Antiinfectives For Systemic Use | Microbial infections | SARS Coronavirus-2 | BavPat1 | NA | RT-PCR | Decrease (90 %) | Approved | 32438446 |
DrugRepV_7568 | Nelfinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | NA | NA | RT-PCR | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7602 | Lopinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | NA | NA | RT-PCR | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7603 | Lopinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | NA | NA | RT-PCR | Decrease (90 %) | Approved | 32438446 |
DrugRepV_7620 | Umifenovir | Antiinfectives For Systemic Use | Prophylaxis/treatment of influenza in Russia and China | SARS Coronavirus-2 | BavPat1 | NA | RT-PCR | Decrease (50 %) | Investigational | 32438446 |
DrugRepV_7621 | Umifenovir | Antiinfectives For Systemic Use | Prophylaxis/treatment of influenza in Russia and China | SARS Coronavirus-2 | BavPat1 | NA | RT-PCR | Decrease (90 %) | Investigational | 32438446 |
DrugRepV_7622 | Anidulafungin | Antiinfectives For Systemic Use | Invasive candidiasis/candidaemia | SARS Coronavirus-2 | ?CoV/KOR/KCDC03/2020) | NA | Immunofluorescence | Decrease (50 %) | Approved, Investigational | 32438446 |
DrugRepV_7623 | Anidulafungin | Antiinfectives For Systemic Use | Invasive candidiasis/candidaemia | SARS Coronavirus-2 | ?CoV/KOR/KCDC03/2020) | NA | Immunofluorescence | Decrease (90 %) | Approved, Investigational | 32438446 |
DrugRepV_7625 | Lopinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | ?CoV/KOR/KCDC03/2020 | NA | Immunofluorescence | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7626 | Lopinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | ?CoV/KOR/KCDC03/2020 | NA | Immunofluorescence | Decrease (90 %) | Approved | 32438446 |
DrugRepV_7629 | Saquinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | NA | NA | RT-PCR | Decrease (50 %) | Approved, Investigational | 32438446 |
DrugRepV_7630 | Saquinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | NA | NA | RT-PCR | Decrease (90 %) | Approved, Investigational | 32438446 |
DrugRepV_7633 | Ritonavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | NA | NA | RT-PCR | Decrease (50 %) | Approved, Investigational | 32438446 |
DrugRepV_7634 | Ritonavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | NA | NA | RT-PCR | Decrease (90 %) | Approved, Investigational | 32438446 |
DrugRepV_7635 | Atazanavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | NA | NA | RT-PCR | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7636 | Atazanavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | NA | NA | RT-PCR | Decrease (90 %) | Approved | 32438446 |
DrugRepV_7643 | Tipranavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | NA | NA | RT-PCR | Decrease (50 %) | Approved, Investigational | 32438446 |
DrugRepV_7644 | Tipranavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | NA | NA | RT-PCR | Decrease (90 %) | Approved, Investigational | 32438446 |
DrugRepV_7645 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | BavPat1 | NA | RT-PCR | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7646 | Dolutegravir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | BavPat1 | NA | RT-PCR | Decrease (90 %) | Approved | 32438446 |
DrugRepV_7647 | Lopinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | ?CoV/KOR/KCDC03/2020) | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7648 | Lopinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | ?CoV/KOR/KCDC03/2020) | NA | Cytopathic effect (CPE) assay | Decrease (90 %) | Approved | 32438446 |
DrugRepV_7652 | Amprenavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | NA | NA | RT-PCR | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7653 | Amprenavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | NA | NA | RT-PCR | Decrease (90 %) | Approved | 32438446 |
DrugRepV_7655 | Penciclovir | Antiinfectives For Systemic Use | Recurrent cold sores on the lips and face from Herpesvirus invections | SARS Coronavirus-2 | Wuhan/WIV04/2019 | NA | qRT-PCR/ NP expression/Immunofluorescence | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7656 | Penciclovir | Antiinfectives For Systemic Use | Recurrent cold sores on the lips and face from Herpesvirus invections | SARS Coronavirus-2 | Wuhan/WIV04/2019 | NA | qRT-PCR/ NP expression/Immunofluorescence | Decrease (90 %) | Approved | 32438446 |
DrugRepV_7657 | Darunavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | NA | NA | RT-PCR | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7658 | Darunavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | NA | NA | RT-PCR | Decrease (90 %) | Approved | 32438446 |
DrugRepV_7659 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | SARS Coronavirus-2 | Wuhan/WIV04/2022 | NA | qRT-PCR/ NP expression/Immunofluorescence | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7660 | Ribavirin | Antiinfectives For Systemic Use | Hepatitis C virus | SARS Coronavirus-2 | Wuhan/WIV04/2022 | NA | qRT-PCR/ NP expression/Immunofluorescence | Decrease (90 %) | Approved | 32438446 |
DrugRepV_7661 | Indinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | NA | NA | RT-PCR | Decrease (50 %) | Approved | 32438446 |
DrugRepV_7662 | Indinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | NA | NA | RT-PCR | Decrease (90 %) | Approved | 32438446 |
DrugRepV_7680 | Clofazamine | Antiinfectives For Systemic Use | Lepromatous leprosy | SARS Coronavirus-2 | NA | NA | NA | Decrease (50 %) | Approved | 32577649 |
DrugRepV_7682 | Entecavir | Antiinfectives For Systemic Use | Hepatitis B virus | SARS Coronavirus-2 | | NA | NA | Decrease (50 %) | Approved | 32577649 |
DrugRepV_7708 | Lopinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | | NA | Plaque reduction assay | Decrease (50 %) | Approved | 32532085 |
DrugRepV_7712 | Clofazimine | Antiinfectives For Systemic Use | Lepromatous leprosy | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | Approved | 32707573 |
DrugRepV_7726 | Clofazimine | Antiinfectives For Systemic Use | Lepromatous leprosy | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | Approved | 32707573 |
DrugRepV_7754 | Clofazimine | Antiinfectives For Systemic Use | Lepromatous leprosy | SARS Coronavirus-2 | SARS-CoV-2-USA-WA1/2020 | NA | Immunofluorescence | Decrease (50 %) | Approved | 32707573 |
DrugRepV_7774 | Ritonavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | NA | NA | NA | Decrease (50 %) | Approved, Investigational | 32687696 |
DrugRepV_8144 | Idoxuridine | Antiinfectives For Systemic Use | Keratoconjunctivitis and Keratitis caused by herpes simplex virus | Vaccinia virus | NA | | NA | Decrease (85.8 %) | Approved, Investigational | 32708182 |
DrugRepV_8167 | Adefovir dipivoxil | Antiinfectives For Systemic Use | Hepatitis B virus | Vaccinia virus | NA | | NA | Decrease (99.8 %) | Approved | 32708182 |
DrugRepV_8193 | AT13387 | Antiinfectives For Systemic Use | Hepatitis C virus | Vaccinia virus | NA | | NA | Decrease (99.8 %) | Phase III | 32708182 |
DrugRepV_8277 | Asunaprevir | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | NA | NA | MTT assay | Decrease (50 %) | Phase III | 32488021 |
DrugRepV_8278 | Simeprevir | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | NA | NA | MTT assay | Decrease (50 %) | Approved | 32488021 |
DrugRepV_8299 | Efavirenz | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Zika virus | Paraiba_01 | NA | Plaque assay | Decrease (50 %) | NA | 32326119 |
DrugRepV_8300 | Efavirenz | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Zika virus | MR-766 | NA | Plaque assay | Decrease (50 %) | NA | 32326119 |
DrugRepV_8301 | Efavirenz | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | West Nile virus | Eg101 | | Plaque assay | Decrease (50 %) | NA | 32326119 |
DrugRepV_8302 | Efavirenz | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | West Nile virus | 13-104 | | Plaque assay | Decrease (50 %) | NA | 32326119 |
DrugRepV_8303 | Tipranavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Zika virus | Paraiba_01 | NA | Plaque assay | Decrease (50 %) | Approved, Investigational | 32326119 |
DrugRepV_8304 | Tipranavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Zika virus | MR-766 | NA | Plaque assay | Decrease (50 %) | Approved, Investigational | 32326119 |
DrugRepV_8305 | Tipranavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | West Nile virus | Eg101 | | Plaque assay | Decrease (50 %) | Approved, Investigational | 32326119 |
DrugRepV_8306 | Tipranavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | West Nile virus | 13-104 | | Plaque assay | Decrease (50 %) | Approved, Investigational | 32326119 |
DrugRepV_8307 | Dasabuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | Paraiba_01 | NA | Plaque assay | Decrease (50 %) | Approved | 32326119 |
DrugRepV_8308 | Dasabuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Zika virus | MR-766 | NA | Plaque assay | Decrease (50 %) | Approved | 32326119 |
DrugRepV_8309 | Dasabuvir | Antiinfectives For Systemic Use | Hepatitis C virus | West Nile virus | Eg101 | | Plaque assay | Decrease (50 %) | Approved | 32326119 |
DrugRepV_8310 | Dasabuvir | Antiinfectives For Systemic Use | Hepatitis C virus | West Nile virus | 13-104 | | Plaque assay | Decrease (50 %) | Approved | 32326119 |
DrugRepV_8326 | Tenofovir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | Experimental | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved, Investigational | 32429580 |
DrugRepV_8330 | Lamivudine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | Hepatitis B virus | SARS Coronavirus-2 | Experimental | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 32429580 |
DrugRepV_8332 | Emtricitabine | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | Experimental | NA | Cytopathic effect (CPE) assay | Decrease (50 %) | Approved | 32429580 |
DrugRepV_8338 | Nelfinavir | Antiinfectives For Systemic Use | Acquired immunodeficiency syndrome | SARS Coronavirus-2 | NA | NA | NA | Decrease (100 %) | Approved | 32374457 |
DrugRepV_8451 | Sofosbuvir | Antiinfectives For Systemic Use | Hepatitis C virus | Acquired immunodeficiency syndrome | Yellow fever virus | YFV17D | | NA | Decrease (50 %) | Approved | 30699122 |
DrugRepV_8452 | Itraconazole | Antiinfectives For Systemic Use | Fungal infections (Pulmonary and extrapulmonary blastomycosis, Histoplasmosis, Aspergillosis, and Onychomycosis) | Influenza virus | PR8M | | MTT assay | Decrease (50 %) | Approved, Investigational | 30866762 |
DrugRepV_8453 | Itraconazole | Antiinfectives For Systemic Use | Fungal infections (Pulmonary and extrapulmonary blastomycosis, Histoplasmosis, Aspergillosis, and Onychomycosis) | Influenza virus | PR8M | | MTT assay | Decrease (90 %) | Approved, Investigational | 30866762 |
DrugRepV_8454 | Posaconazole | Antiinfectives For Systemic Use | Fungal infections (Aspergillus and Candida infections) | Influenza virus | PR8M | | MTT assay | Decrease (50 %) | Approved, Investigational, Vet approved | 30866762 |
DrugRepV_8455 | Posaconazole | Antiinfectives For Systemic Use | Fungal infections (Aspergillus and Candida infections) | Influenza virus | PR8M | | MTT assay | Decrease (90 %) | Approved, Investigational, Vet approved | 30866762 |